Basic information
- CAS
158013-42-4- Standard SMILES
CN1CCN(c2ccc3nc(-c4ccc5nc(-c6cccc(I)c6)[nH]c5c4)[nH]c3c2)CC1- InChIKey
ZEXOKHKEQNNOBG-UHFFFAOYSA-N- Molecular formula
- C25H23IN6
- Average molar mass
- 534.4 g/mol
- Monoisotopic mass
- 534.10289
Names & identifiers
- Preferred name
- meta-iodoHoechst 33258
- IUPAC
- 2-(3-iodophenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
- English name
- meta-iodoHoechst 33258
- Molecular formula
- C25H23IN6
- Molecular weight
- 534.39
Names & synonyms
meta-iodoHoechst 33258158013-42-42-(3-iodophenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazoleMetaiodohoechstCS-1310meta-iodoHoechst33258orb1706344SCHEMBL26252728DTXSID20935845MFCD25976767AKOS030526596DA-55357
Show more names
iodoHoechst 332582,6'-Bi-1H-benzimidazole, 2'-(3-iodophenyl)-6-(4-methyl-1-piperazinyl)-
HY-15622MS-29872F84925T190262'-(3-Iodophenyl)-6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bi-1,3-benzimidazole2'-(3-Iodophenyl)-6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzimidazole
Database identifiers
- CAS
158013-42-4- PubChem CID
- 449492
- DTXSID
DTXSID20935845- Nikkaji
- J1.285.997J
Properties
Computed structural properties
- XLogP
- 5
- Topological polar surface area
- 63.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 642
Physicochemical properties
- Boiling point
- 752.5 · 752.5±70.0 °C(Predicted)
- Density
- 1.587 · 1.587±0.06 g/cm3(Predicted)
- solubility
- 25 ℃: · 25℃: DMSO or water Protect from light
- form
- Powder
- pka
- 10.66 · 10.66±0.10(Predicted)
- color
- Off-white to pink
- Appearance
- Solid Powder
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
DescriptionMeta-iodoHoechst 33258, an iodinated DNA-binding bibenzimidazole, is a cell dye for DNA quantitation which sensitizes DNA and cells to UVA.
Usesmeta-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Suppliers14 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
河南闰霖化工有限公司+86-18738066252; +86-18738066252 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
天津凯利奇生物科技有限公司15076683720 · [email protected]
Musechem+1-800-259-7612 · [email protected]
ChemeGen 中国18818260767 · [email protected]
烟台盛凯伦化学科技有限公司开发区第一分公司13356901049 · [email protected]
上海皓元医药股份有限公司021-58950125 · [email protected]
上海安能健生物医药科技有限公司021-68781987 13818305065 · [email protected]
上海弘渠生物医药科技有限公司88888888888 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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