Basic information
- CAS
53179-07-0- Standard SMILES
CNCCC(Oc1ccccc1OC)c1ccccc1- InChIKey
ITJNARMNRKSWTA-UHFFFAOYSA-N- Molecular formula
- C17H21NO2
- Average molar mass
- 271.35 g/mol
- Monoisotopic mass
- 271.15722891
Overview
Nisoxetine is a secondary amino compound that is N-methyl-3-phenylpropan-1-amine substituted at position 3 by a 2-methoxyphenoxy group. It has a role as an antidepressant and an adrenergic uptake inhibitor. It is an aromatic ether and a secondary amino compound.
Names & identifiers
- Preferred name
- Nisoxetine
- IUPAC
- 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine
- English name
- nisoxetine
- Molecular formula
- C17H21NO2
- Molecular weight
- 271.35414
Names & synonyms
Nisoxetine53179-07-03-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amineNisoxetinaCompound 89218Nisoxetinum3-(2-Methoxyphenoxy)-N-methyl-3-phenylpropylamineDTXSID0045175COMPOUND-89218NSC-28348117NV064B2DDL-N-Methyl-3-(o-methoxyphenoxy)-N-methyl-3-phenylpropylamine
Show more names
3-(o-Methoxyphenoxy)-N-methyl-3-phenylpropylamineN-Methyl-gamma-(2-methylphenoxy)phenylpropanolamineDTXCID8025175CHEBI:73410LY 94939RefChem:85420657226-61-6CHEMBL295467
Database identifiers
- CAS
53179-07-0、57226-61-6- PubChem CID
- 4500
- DTXSID
DTXSID0045175- ChEMBL
CHEMBL295467- ChEBI
CHEBI:73410- UNII
- 17NV064B2D
Properties
Computed structural properties
- XLogP
- 3.1
- Topological polar surface area
- 30.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 7
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 253
Experimental & physicochemical properties
Chemical ClassesOther Uses -> Biochemical Research
Chemistry & industry
Uses & manufacturing
UsesPotent inhibitor for norepinephrine uptake into rat brain synaptosomes & brain. [ChemIDplus]
Suppliers14 total
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
武汉壹加壹生物科技有限公司027-027-16602739303 16602739303 · [email protected]
杭州六可生物科技有限公司+86-0571-86912261 +86-15658003402 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
上海芮晖化工科技有限公司021-31433387 15618786686 · [email protected]
上海超岚化工科技中心QQ：65489617 13301690235 · [email protected]
ATK CHEMICAL COMPANY LIMITED+undefined-21-51877795 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Related reactions
8 records
Compound notes
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