3'-Azido-3'-deoxyarabinothymidine
Basic information
- CAS
99614-77-4- Standard SMILES
Cc1cn([C@@H]2O[C@H](CO)[C@@H](N=[N+]=[N-])[C@@H]2O)c(=O)[nH]c1=O- InChIKey
DVRKESVZZVYJRB-JAGXHNFQSA-N- Molecular formula
- C10H13N5O5
- Average molar mass
- 283.24 g/mol
- Monoisotopic mass
- 283.09166853
Overview
structure given in first source
Names & identifiers
- Preferred name
- 3'-Azido-3'-deoxyarabinothymidine
- IUPAC
- 1-[(2R,3S,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- English name
- 3'-azido-3'-deoxyarabinothymidine
- Molecular formula
- C10H13N5O5
- Molecular weight
- 283.24
Names & synonyms
3'-Azido-3'-deoxyarabinothymidine3-Adat99614-77-4RefChem:903181-[(2R,3S,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione3'-N3-araT3'-Azido-2'-ara-thymineDTXSID809125961-(3-Azido-3-deoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one1-(3-Azido-3-deoxy-beta-D-arabinofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one2,4(1H,3H)-Pyrimidinedione, 1-(3-azido-3-deoxy-beta-D-arabinofuranosyl)-5-methyl-1-[(2R,3S,4S,5S)-4-azido-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
Show more names
1-(3-azido-3-deoxy-β-D-arabinofuranosyl)thymine
2,4(1H,3H)-Pyrimidinedione, 1-(3-azido-3-deoxy-.beta.-D-arabinofuranosyl)-5-methyl-3'-Azido-2'-ara-thymine
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- -0.9
- Topological polar surface area
- 113 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 3
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 514
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
Related reactions
0 records
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Compound notes
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