Glycinamide, glycyl-prolyl-
Basic information
- CAS
141497-12-3- Standard SMILES
NCC(=O)N1CCC[C@H]1C(=O)NCC(N)=O- InChIKey
JWWLMJFURJYNEX-LURJTMIESA-N- Molecular formula
- C9H16N4O3
- Average molar mass
- 228.25 g/mol
- Monoisotopic mass
- 228.12224039
Overview
structure in first source
Names & identifiers
- Preferred name
- Glycinamide, glycyl-prolyl-
- IUPAC
- (2S)-1-(2-aminoacetyl)-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide
- English name
- H-GLY-PRO-GLY-NH2 HCL
- Molecular formula
- C9H16N4O3
- Molecular weight
- 228.25
Names & synonyms
141497-12-3Glycinamide, glycyl-L-prolyl-GPG-NH2Glycylprolylglycine AmideGlycyl-prolyl-glycyl amideGly-pro-gly-NH2Glycinamide, glycyl-prolyl-(2S)-1-(2-aminoacetyl)-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamideGlycyl-L-prolylglycinamideglycyl-prolyl-glycine amide73GV270Z6Z(2s)-1-(aminoacetyl)-n-(carbamoylmethyl)pyrrolidine-2-carboxamide
Show more names
H-GLY-PRO-GLY-NH2 HCLH-Gly-Pro-Gly-NH2 hydrochloride
RefChem:201090H-Gly-Pro-Gly-NH2(S)-N-(2-Amino-2-oxoethyl)-1-glycylpyrrolidine-2-carboxamideH-Gly-Pro-Gly-NH2 . HClglycyl-prolyl-glycinamideH-Gly-Pro-Gly-NH2.HClGlycinamide, glycyl-L-prolylUNII-73GV270Z6Z
Database identifiers
- CAS
141497-12-3- PubChem CID
- 456396
- UNII
- 73GV270Z6Z
- Nikkaji
- J3.504.659C
Properties
Computed structural properties
- XLogP
- -3.2
- Topological polar surface area
- 119 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 305
Physicochemical properties
- Boiling point
- 618 · 618.0±55.0 °C(Predicted)
- Density
- 1.326 · 1.326±0.06 g/cm3(Predicted)
- storage temp.
- -15 °C · -15°C
- pka
- 14.27 · 14.27±0.20(Predicted)
- Sequence
- 2 · H-Gly-Pro-Gly-NH2 · HCl
- FDA UNII
- 73 GV270Z6Z · 73GV270Z6Z
Chemistry & industry
Applications
UsesH-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 IIIB and HIV-2 ROD with EC50 values of 35 μM and 30 μM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research[1][2][3].
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Compound notes
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