1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione

HCID 458487CAS 1585-90-6

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Basic information

Standard SMILES: O=C1C=CC(=O)N1CCO
InChIKey: AXTADRUCVAUCRS-UHFFFAOYSA-N
Molecular formula: C6H7NO3
Average molar mass: 141.126 g/mol
Monoisotopic mass: 141.04259308

Names & identifiers

Preferred name: 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione
IUPAC: 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione
English name: 1-(2-HYDROXY-ETHYL)-PYRROLE-2,5-DIONE
Molecular formula: C6H7NO3
Molecular weight: 141.12

Names & synonyms

1-(2-hydroxyethyl)-1H-pyrrole-2,5-dioneHEMIN-(2-HYDROXYETHYL)MALEIMIDEN-(Ethanol)maleimideN-Hydroxyethyl MaleiMideN-hydroxyethylMaleiciMide1-(2-Hydroxyethyl)maleimideN-(2-Hydroxyethyl)MaleiMide,99%N-(2-Hydroxyethyl)MaleiMide 97%1-(2-HYDROXY-ETHYL)-PYRROLE-2,5-DIONE

Database identifiers

CAS: 1585-90-6
PubChem CID: 458487
DTXSID: DTXSID70332522
EC Number: 696-457-4
Nikkaji: J1.049.861I

Properties

Physicochemical properties

Melting point: 66 · 66-67 °C (lit.) 67-74 °C
Boiling point: 130 °C/0.005mmHg · 130°C/0.005mmHg(lit.)
Density: 1.395 · 1.395
storage temp.: 2 · 2-8°C
form: Powder
pka: 14.21 · 14.21±0.10(Predicted)
color: white
InChI: InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2
InChIKey: AXTADRUCVAUCRS-UHFFFAOYSA-N
SMILES: N1(CCO)C(=O)C=CC1=O
CAS DataBase Reference: 1585 · 1585-90-6
UNSPSC Code: 12352111 · 12352111
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 319 · H319
Precautionary statements: 305 · P305+P351+P338
Hazard Codes: Xn
Risk Statements: 22 · 22-36
Safety Statements: 26 · 26
WGK Germany: 3 · 3
HS Code: 2925.19 · 2925.19.9100

Safety & regulation

Safety data

wgk: 3
hs_code: 2925.19.9100
risk_code: 22-36
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xn
safety_code: 26
Hazard statements: H319
Precautionary statements: P305+P351+P338

Chemistry & industry

Applications

Description1-(2-hydroxymethyl)-1-H-pyrrole-2,5-dione is a synthetic building block for adding an maleimide group with a hydroxyl handle. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Uses1-(2-Hydroxy-ethyl)-pyrrole-2,5-dione is a substituted succinimide with antibacterial and cytotoxic activities.