Basic information
- CAS
6000-44-8- Standard SMILES
NCC(=O)[O-].[Na+]- InChIKey
WUWHFEHKUQVYLF-UHFFFAOYSA-M- Molecular formula
- Na-C2-H4-N-O2
- Average molar mass
- 97.05 g/mol
- Monoisotopic mass
- 97.01397265
Overview
See also: Glycine (annotation moved to); N-(4-Hydroxyphenyl)glycine (annotation moved to).
Names & identifiers
- Preferred name
- Sodium Glycinate
- IUPAC
- sodium 2-aminoacetate
- English name
- Sodium glycinate
- Molecular formula
- C2H6NNaO2
- Molecular weight
- 99.06
Names & synonyms
Sodium glycinateGlycine, monosodium saltSodium glycineSodium aminoacetateSodium glycocollateGlycine, sodium salt (1:1)ORISTAR SGLYF6B979BV8ZDTXSID50884211RefChem:183897DTXCID701023666227-842-3
Show more names
H-Gly-ONaGlycocollglycocollateGlycine sodiusodiumglycineGlycine SodumGlycine sodiumGlycine sldiumSodium glycite
6000-44-8sodium 2-aminoacetateGlycine sodium saltSodum glycinatesodium;2-aminoacetateGLYCINE, SODIUM SALTEINECS 227-842-3MFCD00062543
Database identifiers
- CAS
6000-44-8- PubChem CID
- 4684308
- DTXSID
DTXSID50884211- UNII
- F6B979BV8Z
- EC Number
- 227-842-3
- Nikkaji
- J21.903G
Properties
Computed structural properties
- Topological polar surface area
- 66.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 46.8
Experimental & physicochemical properties
Chemical ClassesBiological Agents -> Amino Acids and Derivatives
CosmeticsCosmetic ingredients (Sodium Glycinate) -> CIR (Cosmetic Ingredient Review)
Physical Description
Liquid
Solid; [Sigma-Aldrich MSDS]
Physicochemical properties
- Boiling point
- 321 ℃[at · 321℃[at 101 325 Pa]
- Density
- 1.333 · 1.333[at 20℃]
- refractive index
- 1.491 · 1.491
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Moist Beads
- pka
- 4.3 · 4.3[at 20 ℃]
- color
- White to yellow
- Odor
- Odorless
- Viscosity
- 13.33 mm2/s · 13.33mm2/s
- Cosmetics Ingredients Functions
- SKIN CONDITIONING
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (88 of 88) of all reports.
Not Classified
Aggregated GHS information provided per 88 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: Glycine, monosodium salt
Glycine, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Glycine, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 10-10-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/24213
Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Hazards SummaryIntravenous LD50 (mouse) = 564 mg/kg; [RTECS] May cause irritation; [Sigma-Aldrich MSDS] See Glycine.
Hazard Classes and CategoriesNot Classified
Safety & protection
Protective Action Criteria (PAC)
1.8 [mg/m3]
20 [mg/m3]
120 [mg/m3]
Toxicology
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
Uses & manufacturing
UsesCIR ingredient: Sodium Glycinate
U.S. Production2023: 1,900,000 lb
Industry UsesIntermediate
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Glycine, sodium salt (1:1): ACTIVE
Applications
DescriptionSodium glycinate is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
UsesSodum glycinate is a useful research chemical. It Inhibits spinal cord neurotransmitter, allosteric regulator of NMDA receptors.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
82 records
Compound notes
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