Cianopramine
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Basic information
- CAS
66834-24-0- Standard SMILES
CN(C)CCCN1c2ccccc2CCc2ccc(C#N)cc21- InChIKey
LQXYCDLHSKICDY-UHFFFAOYSA-N- Molecular formula
- C20H23N3
- Average molar mass
- 305.4 g/mol
- Monoisotopic mass
- 305.18919775
Overview
Cianopramine is a small molecule drug. The usage of the INN stem '-pramine' in the name indicates that Cianopramine is a substance of the imipramine group. Cianopramine has a monoisotopic molecular weight of 305.19 Da.
Names & identifiers
- Preferred name
- Cianopramine
- IUPAC
- 11-[3-(dimethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepine-2-carbonitrile
- English name
- Cianopramine
- Molecular formula
- C20H23N3
- Molecular weight
- 305.42
Names & synonyms
CIANOPRAMINE66834-24-0CianopraminaCianopraminum3-cyano-imipramine02MNR4P2PMRO 11-2464DTXSID902169563-cyanoimipramine5H-Dibenz(b,f)azepine-3-carbonitrile, 5-(3-(dimethylamino)propyl)-10,11-dihydro-RefChem:126081DTXCID20139447
Show more names
Ro-11-2465Cyanimipramine5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine-3-carbonitrile5H-Dibenz[b,f]azepine-3-carbonitrile, 5-[3-(dimethylamino)propyl]-10,11-dihydro-
5-(3 (dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine-3-carbonitrilecyanoimipramineCianopramine [INN]Cyanimipramine; Ro 11-246511-[3-(dimethylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepine-2-carbonitrile5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine-3-carbonitrileCianopraminum [INN-Latin]5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenzo[b,f]azepine-3-carbonitrile
Database identifiers
- CAS
66834-24-0- PubChem CID
- 48126
Properties
Computed structural propertiesFilling in
- XLogP
- 4.3
- Topological polar surface area
- 30.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 4
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 424
Physicochemical properties
- Boiling point
- 456.4 · 456.4±45.0 °C(Predicted)
- Density
- 1.14 · 1.14±0.1 g/cm3(Predicted)
- pka
- 9.45 · 9.45±0.28(Predicted)
- FDA UNII
- 2 MNR4P2PM · 02MNR4P2PM
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationDrugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.
Applications
UsesCianopramine (Cyanimipramine) is a tricyclic antidepressant, and a potent inhibitor of neuronal serotonin (5-HT) uptake. Cianopramine blocks central and peripheral 5-HT receptors[1][2].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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