Glu-P 2
Basic information
- CAS
67730-10-3- Standard SMILES
Nc1ccc2nc3ccccn3c2n1- InChIKey
BUXVIXBGMQXWGT-UHFFFAOYSA-N- Molecular formula
- C10H8N4
- Average molar mass
- 184.2 g/mol
- Monoisotopic mass
- 184.07489627
Overview
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).
Names & identifiers
- Preferred name
- Glu-P 2
- IUPAC
- 1,3,8-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8,10,12-hexaen-4-amine
- English name
- 2-Aminodipyrido[1,2-a:3',2-d]imidazole, hydrochloride
- Molecular formula
- C10H8N4
- Molecular weight
- 184.2
Names & synonyms
67730-10-3Glu-P-22-Aminodipyrido[1,2-a:3',2'-d]imidazole2-AMINODIPYRIDO(1,2-A:3',2'-D)IMIDAZOLEDipyrido(1,2-a:3',2'-d)imidazol-2-amineDipyrido[1,2-a:3',2'-d]imidazol-2-amineGLU-P 2DTXSID0020658N79505HO3L2-aminodipyridoimidazoleGlu P-21,3,8-triazatricyclo(7.4.0.0^(2,7))trideca-2,4,6,8,10,12-hexaen-4-amine
Show more names
Ccris 28Brn 06449122-a:3’,2’-d)imidazole,2-amino-dipyrido(dipyrido(1,2-a:3’,2’-d)imidazol-2-amine2-amino-dipyrido(1,2-a:3’,2’-d)-imidazole2-Aminodipyrido[1.2-a.3'.2-d]imidazoleHClDipyrido(1,2-A:3',2'-D)imidazole, 2-amino-2-AMINODIPYRIDO[1,2-A:3',2'-D]IMIDAZOLE HYDROCHLORIDE
1,3,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8,10,12-hexaen-4-amine2-aminodipyrido(1,2-a-3',2'-d)imidazoleRefChem:663084DTXCID00658imidazo[1,2-a:5,4-b']dipyridin-2-amine2-Aminodipyridol(1,2-a:3',2'-d)imidazole2-Amino-dipyrido(1,2-a:3',2'-d)-imidazolepyrido[3',2':4,5]imidazo[1,2-a]pyridin-2-amine
Database identifiers
- CAS
67730-10-3- PubChem CID
- 49970
- DTXSID
DTXSID0020658- ChEBI
CHEBI:82331- UNII
- N79505HO3L
- EC Number
- 689-086-4
- Nikkaji
- J45.285H
Properties
Computed structural properties
- XLogP
- 1.4
- Topological polar surface area
- 56.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 220
Experimental & physicochemical properties
LogP
1.38
1.38
Physicochemical properties
- Melting point
- 300 °C · 300°C
- Boiling point
- 308.15 °C · 308.15°C (rough estimate)
- Density
- 1.2729 · 1.2729 (rough estimate)
- refractive index
- 1.52 · 1.5200 (estimate)
- CAS DataBase Reference
- 67730 · 67730-10-3
- EWG's Food Scores
- 2 · 2
- FDA UNII
- 79505 HO3L · N79505HO3L
- Proposition 65 List
- -2 · Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
- IARC
- 2 B · 2B (Vol. 40, Sup 7) 1987
- EPA Substance Registry System
- 2 · 2-Aminodipyrido[1,2-a:3',2'-d]imidazole (67730-10-3)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Regulatory InformationHazard Traits - Carcinogenicity
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Toxicology
Carcinogen Classification
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
Group 2B: Possibly carcinogenic to humans
Volume 40: (1986) Some Naturally Occurring and Synthetic Food Components, Furocoumarins and Ultraviolet Radiation
1987
1987
RAIS Toxicity Values
0.0004
CALEPA
1.4
CALEPA
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- Hazard statements
- H335-H319-H315
- Precautionary statements
- P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
Cellular LocationsCytoplasm
Applications
UsesGlu-P-2 is highly mutagenic in the Ames test. Studies have shown that broiled fish, fried beef, commercial beef extracts and protein pyrolsylates contain this mutagen
Additional notes
DefinitionChEBI: Glu-P-2 is an imidazopyridine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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