Basic information
- CAS
67076-74-8- Standard SMILES
CCCCCC[C@H]1OC(=O)CNC(=O)[C@@H]([C@H](C)O)NC(=O)[C@@H](CO)NC(=O)[C@H]([C@H](C)CC)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H]1C- InChIKey
VFGBXFZXJAWPOE-UEMXSQFKSA-N- Molecular formula
- C32H57N5O9
- Average molar mass
- 655.8 g/mol
- Monoisotopic mass
- 655.41562841
Names & identifiers
- Preferred name
- (6R,9R,12S,15S,18R,19R)-19-hexyl-6-[(1S)-1-hydroxyethyl]-9-(hydroxymethyl)-15-isobutyl-16,18-dimethyl-12-[(1R)-1-methylpropyl]-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
- IUPAC
- (6R,9R,12S,15S,18R,19R)-12-[(2R)-butan-2-yl]-19-hexyl-6-[(1S)-1-hydroxyethyl]-9-(hydroxymethyl)-16,18-dimethyl-15-(2-methylpropyl)-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone
- English name
- globomycin
- Molecular formula
- C32H57N5O9
- Molecular weight
- 655.82
Names & synonyms
Globomycin from streptomyces hagronensis(6R,9R,12S,15S,18R,19R)-19-hexyl-6-[(1S)-1-hydroxyethyl]-9-(hydroxymethyl)-15-isobutyl-16,18-dimethyl-12-[(1R)-1-methylpropyl]-1-oxa-4,7,10,13,16-pentazacyclononadecane-2,5,8,11,14,17-hexone6-((1R)-1-Methylpropyl)-12-((1S)-1-hydroxyethyl)(3S,6S,9R,12R,18R,19R)-18-hexyl-9-(hydroxymethyl)-2,19-dimethyl-3-(2-methylpropyl)-17-oxa-2,5,8,11,14-pentaazacyclononadecane-1,4,7,10,13,16-hexaoneSF 1902SF-1902A1globomycinAntibiotic SF-1902A1Cyclo[Gly-[(2R,3R)-3-hydroxy*-2-methyl-1-oxononyl]-N-methyl-L-Leu-L-aIle-L-Ser-L-aThr-]Cyclo[L-alloisoleucyl-L-seryl-L-allothreonylglycyl-(2R,3R)-3-hydroxy-2-methylnonanoyl-N-methyl-L-leucyl]Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxononyl)-N-methylleucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone
Database identifiers
- CAS
67076-74-8- PubChem CID
- 508500
Properties
Computed structural properties
- XLogP
- 3.9
- Topological polar surface area
- 203 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 11
- Heavy atoms
- 46
- Formal charge
- 0
- Complexity
- 1,040
Physicochemical properties
- Melting point
- 105 · 105-108 °C
- Boiling point
- 987.8 · 987.8±65.0 °C(Predicted)
- Density
- 1.062 · 1.062±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- 1 mg/mL · DMSO: soluble1mg/mL
- form
- powder
- pka
- 12.79 · 12.79±0.70(Predicted)
- color
- white
- WGK Germany
- 3 · 3
- RTECS
- 593500 · MC0593500
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- rtecs
- MC0593500
Chemistry & industry
Applications
UsesGlobomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM[1][2].
Suppliers3 total
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
南昌探真生物技术有限公司13758194781 13173652190 · [email protected]
Additional notes
DefinitionChEBI: Globomycin is a cyclodepsipeptide.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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