Beclobrate

HCID 51348
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Basic information

CAS
55937-99-0
Standard SMILES
CCOC(=O)C(C)(CC)Oc1ccc(Cc2ccc(Cl)cc2)cc1
InChIKey
YWQGBCXVCXMSLJ-UHFFFAOYSA-N
Molecular formula
C20H23ClO3
Average molar mass
346.8 g/mol
Monoisotopic mass
346.13357228

Overview

Beclobrate is a diarylmethane.

Names & identifiers

Preferred name
Beclobrate
IUPAC
ethyl 2-[4-[(4-chlorophenyl)methyl]phenoxy]-2-methylbutanoate
English name
Beclobrate
Molecular formula
C20H23ClO3
Molecular weight
346.85

Names & synonyms

Beclobrate55937-99-0BeclobratoBeclobratumUSZ5MY269RDTXSID101021600Butanoic acid, 2-(4-((4-chlorophenyl)methyl)phenoxy)-2-methyl-, ethyl ester, (+-)-RefChem:116862DTXCID5015066122-(4-((4-chlorophenyl)methyl)phenoxy)-2-methylbutanoic acid ethyl ester259-912-4Ethyl 2-(4-(4-chlorobenzyl)phenoxy)-2-methylbutanoate
Show more names
Beclobrate USP/EP/BPEthyl(±)-2-[[α(-(4-chlorophenyl)-4-tolyl]oxy]-2-methylbutyrate2-[4-(4-Chlorobenzyl)phenoxy]-2-methylbutyric acid ethyl esterButanoic acid, 2-[4-[(4-chlorophenyl)Methyl]phenoxy]-2-Methyl-, ethyl ester
Sgd 24774ethyl 2-[4-[(4-chlorophenyl)methyl]phenoxy]-2-methylbutanoateSgd-24774beclipurEthyl 2-(4-((4-chlorophenyl)methyl)phenoxy)-2-methylbutanoateBeclobrato [Spanish]TurecBeclobratum [INN-Latin]

Database identifiers

CAS
55937-99-0
PubChem CID
51348
DTXSID
DTXSID101021600
ChEMBL
CHEMBL152684
ChEBI
CHEBI:135463
UNII
USZ5MY269R
EC Number
259-912-4
Nikkaji
J65.869C

Properties

Computed structural properties

XLogP
5.8
Topological polar surface area
35.5 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
3
Rotatable bonds
8
Heavy atoms
24

Physicochemical properties

Boiling point
0.01 · bp0.01-0.1 200-204°
storage temp.
2 · 2-8°C
FDA UNII
5 MY269R · USZ5MY269R
Toxicity
50 orally · LD50 orally in mice: 8000 mg/kg (Thiele, 1979)

Safety & regulation

Safety data

Toxicity
LD50 orally in mice: 8000 mg/kg (Thiele, 1979)

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationSubstances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.

Applications

DescriptionBeclobrate is a hypolipidemic agent related structurally to clofibrate. It is reportedly useful in types IIa-V hyperlipoproteinemias, promoting normalization of t h e atherogenic index.

Upstream & downstream products

Suppliers16 total

上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海微佳禾生物科技有限公司17502176150; 17502176150 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
United Life Science020-82099279 18988941402 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]

Additional notes

DefinitionChEBI: Beclobrate is a diarylmethane.

Related reactions

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Compound notes

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