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Basic information
- CAS
138-52-3- Standard SMILES
OCc1ccccc1OC1OC(CO)C(O)C(O)C1O- Molecular formula
- C13H18O7
- Average molar mass
- 286.28 g/mol
Names & identifiers
- Preferred name
- D-(-)-Salicin
- English name
- D-(-)-Salicin
- Molecular formula
- C13H18O7
- Molecular weight
- 286.28
Names & synonyms
SALICIND-SALICINSalicineSALICOSIDEWHITE WILLOWSalicylinSalicin-RMSALICIN(RG)SALICIN(SH)Salicin >
Database identifiers
- CAS
138-52-3- PubChem CID
- 5145
- ChEMBL
CHEMBL315895
Properties
Physicochemical properties
- Melting point
- 196 · 196-202 °C
- alpha
- -61.5 · -61.5 º (c=5, water)
- Boiling point
- 388.65 °C · 388.65°C (rough estimate)
- Density
- 1.434 · 1.4340
- refractive index
- -62 ° · -62 ° (C=3, H2O)
- storage temp.
- 2 · 2-8°C
- solubility
- 36 g/l · 36g/l
- form
- Fine Crystalline Powder
- pka
- 12.8 · 12.80±0.70(Predicted)
- color
- White
- Water Solubility
- 36 g/L · 36 g/L (15 ºC), 250 g/L (60 ºC)
- Merck
- 14 · 14,8324
- BRN
- 89593 · 89593
- Stability
- Stable, but light sensitive. Incompatible with strong oxidizing agents.
- Major Application
- cleaning productscosmeticsflavors and fragrancesfood and beveragespersonal care
- Cosmetics Ingredients Functions
- SKIN CONDITIONING
- InChI
- 1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
- InChIKey
- NGFMICBWJRZIBI-MICYEWLZSA-N
- SMILES
- OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O
- LogP
- -1.232 · -1.232 (est)
- CAS DataBase Reference
- 138 · 138-52-3(CAS DataBase Reference)
- FDA UNII
- 4649620 TBZ · 4649620TBZ
- NIST Chemistry Reference
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 3-10
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- LZ5901700
- hs_code
- 29389090
- risk_code
- 43
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 36/37-37-24/25-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H317
- Hazard Classifications
- Skin Sens. 1
- Precautionary statements
- P280-P302+P352
Chemistry & industry
Applications
DescriptionD(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.
Usesanalgesic, antipyretic
UsesH1 antihistamine (nonsedating)
UsesStandard substrate in evaluating enzyme Preparations contg b-glucosidase: Weidenhagen, Z. Ver. Zucker-Ind. 79, 591 (1929).
UsesD-(-)-Salicin has been used:to study its in vitro anticoagulant and antiplatelet activitiesas a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plantas a tastant in taste threshold assayas a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei
General DescriptionSalicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
Related reactions
0 records
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Compound notes
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