Basic information
- CAS
10049-21-5- Standard SMILES
O.O=P([O-])(O)O.[Na+]- InChIKey
BBMHARZCALWXSL-UHFFFAOYSA-M- Molecular formula
- H4NaO5P
- Average molar mass
- 137.99 g/mol
- Monoisotopic mass
- 137.9694045
Names & identifiers
- Preferred name
- Sodium Phosphate, Monobasic, Monohydrate
- IUPAC
- sodium;dihydrogen phosphate;hydrate
- English name
- Sodium Phosphate Monobasic Monohydrate
- Molecular formula
- H4NaO5P
- Molecular weight
- 137.992291
Names & synonyms
Sodium phosphate monobasic monohydrateSodium dihydrogen phosphate monohydrateMonosodium phosphate monohydrateSodium phosphate monohydratePhosphoric acid, monosodium salt, monohydrateSODIUM PHOSPHATE, MONOBASIC, MONOHYDRATEsodium dihydrogenphosphate monohydrate593YOG76RNDTXSID6073994CHEBI:114249sodium dihydrogen phosphate--water (1/1)MONOBASIC SODIUM PHOSPHATE MONOHYDRATE
Show more names
PHOSPHATE BUFFERPOTASSIUM PHOSPHATE BUFFERPH 7 BUFFERPhosphate bufferedSODIUMPHOSPHATEMONOBASIC,MONOHYDRATE,GRANULAR,USP,BPRIA BUFFERBUFFER FOR BODDilution bottleBUFFER MDB 9.50
MONOBASIC SODIUM PHOSPHATE, MONOHYDRATESODIUM PHOSPHATE MONOBASIC, MONOHYDRATESODIUM PHOSPHATE MONOBASIC (MONOHYDRATE)SODIUM PHOSPHATE, MONOBASIC MONOHYDRATE [MI]SODIUM PHOSPHATE MONOBASIC,MONOHYDRATE [VANDF]SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE [II]SODIUM PHOSPHATE,MONOBASIC,MONOHYDRATE [VANDF]SODIUM PHOSPHATE MONOBASIC (MONOHYDRATE) [WHO-DD]
Properties
Computed structural properties
- Topological polar surface area
- 81.6 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 0
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 61
Experimental & physicochemical properties
Physical Description
Dry Powder
White odorless solid; Slightly deliquescent; [Merck Index] White hygroscopic crystals; [Sigma-Aldrich MSDS]
Physicochemical properties
- Melting point
- 100 °C · 100°C -H₂O
- Boiling point
- 399 °C · 399 °C
- Density
- 2 · 2,04 g/cm3
- bulk density
- 880 kg/m3 · 880kg/m3
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- solubility
- 2 O: · H2O: 1 M, clear, colorless
- form
- Solid
- pka
- 7.21 · 7.21
- color
- White semi-transparentor
- Odor
- Odorless
- PH Range
- 4.1 · 4.1 - 4.5 at 50 g/l at 25 °C
- PH
- 4.1 · 4.1-4.5 (25℃, 50mg/mL in H2O)
- Water Solubility
- Soluble in water; insoluble in ethanol, ether and chloroform.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 76.9% (40 of 52) of all reports.
Warning
H315 (21.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (21.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (21.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 52 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 40 of 52 reports by companies.；There are 4 notifications provided by 12 of 52 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Regulatory Information
Chemical: Phosphoric acid, monosodium salt, monohydrate
Phosphoric acid, monosodium salt, monohydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, monosodium salt, monohydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Monosodium dihydrogen phosphate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Phosphoric acid, monosodium salt, monohydrate: Human health tier I assessment
Chemistry & industry
Uses & manufacturing
UsesUsed in baking powders, boiler water, foods (acidulant and sequestrant), and as a veterinary urinary acidifier; [Merck Index]
U.S. Production2023: 41,887 lb；2022: 14,200 lb；2021: 34,041 lb；2020: 59,762 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesNot Known or Reasonably Ascertainable
Household ProductsInformation on 1 consumer products that contain Sodium phosphate monobasic monohydrate in the following categories is provided:；• Personal Care
General Manufacturing InformationAll Other Chemical Product and Preparation Manufacturing
Applications
DescriptionSodium Phosphate Monobasic Monohydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures. Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. It is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry. It is applied as a fireproofing agent and for weighting silk in tanning. It is employed in manufacturing of enamels, ceramics, detergents, boiler compounds, in soldering and brazing instead of borax. Monobasic sodium phosphate is used in baking powders, acid cleansers, electroplating, as a dry acidulant, and in treating boiler water.
UsesExcipient.
UsesSodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures.
Related reactions
133 records
Compound notes
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