Potassium Acetate

HCID 517044CAS 127-08-2

Basic information

Standard SMILES
CC(=O)[O-].[K+]
InChIKey
SCVFZCLFOSHCOH-UHFFFAOYSA-M
Molecular formula
C2H3KO2
Average molar mass
98.14 g/mol
Monoisotopic mass
97.97701082

Names & identifiers

Preferred name
Potassium Acetate
IUPAC
potassium acetate

Names & synonyms

Potassium acetate127-08-2Diuretic saltACETIC ACID, POTASSIUM SALTAcetic acid, potassium salt (1:1)Potassium ethanoateFEMA No. 2920Octan draselnyKali aceticumPotassium acetatesDTXSID7027043Potassium acetate in plastic container
Show more names
INS NO.261E261INS-261INS-261(I)DTXCID107043E-261M911911U02CHEBI:32029

Database identifiers

CAS
127-08-2
PubChem CID
517044
DTXSID
DTXSID7027043
ChEMBL
CHEMBL1201058
ChEBI
CHEBI:32029
UNII
M911911U02
EC Number
204-822-2、686-264-3
Nikkaji
J2.516J

Properties

Computed structural properties

Topological polar surface area
40.1 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
5

Experimental & physicochemical properties

pH7,5-9,0 (5 % aqueous solution)
Density · 2 items

1.6 g/cm³

1.57 @25 °C

SolubilitySolubility in water, g/100ml at 20 °C: 256
Melting Point · 2 items

292 °C

309 °C

Physical Description · 4 items

CBI; Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals

Colourless, deliquescent crystals or a white crystalline powder, odourless or with a faint acetic odour

Lustrous colorless or white solid; Rapidly deliquescent; [Merck Index] White crystalline solid; [Aldrich MSDS]

WHITE FLAKES OR CRYSTALLINE POWDER.

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 87.3% (418 of 479) of all reports.

Warning

H315 (11.5%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (11.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 479 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 418 of 479 reports by companies.;There are 9 notifications provided by 61 of 479 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 4 items

Chemical: Acetic acid, potassium salt

Acetic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15104

Potassium acetate: Non hazardous

Other Safety InformationIMAP assessments - Acetic acid, potassium salt: Human health tier I assessment
Fire HazardsCombustible.
Hazards SummaryA mild skin and eye irritant; [ICSC] Not irritating to eyes of rabbits; [IUCLID] Allowable daily intake (ADI) of not limited [JECFA] May cause irritation; [Aldrich MSDS]
EPA Safer ChemicalChemical: Potassium acetate; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Chemical DangersDecomposes on heating and on contact with strong acids. This produces acetic acid fumes. Reacts violently with strong oxidants. The solution in water is a weak base.

Safety & protection

Fire FightingUse water spray, foam, powder, carbon dioxide.
First Aid Measures · 4 items

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rest.

Safe StorageSeparated from strong acids and strong oxidants.
Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

Eye PreventionWear safety goggles.
Fire PreventionNO open flames.

Toxicology

Exposure RoutesThe substance can be absorbed into the body by ingestion.
Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Signs and Symptoms · 2 items

Redness.

Redness.

Regulatory information

Regulatory Information · 4 items

Chemical: Acetic acid, potassium salt

Acetic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15104

Potassium acetate: Non hazardous

Chemistry & industry

Pharmacology

ATC Code · 2 items

B - Blood and blood forming organs;B05 - Blood substitutes and perfusion solutions;B05X - I.v. solution additives;B05XA - Electrolyte solutions;B05XA17 - Potassium acetate

QB - Blood and blood forming organs;QB05 - Blood substitutes and perfusion solutions;QB05X - I.v. solution additives;QB05XA - Electrolyte solutions;QB05XA17 - Potassium acetate

Mechanism of Action · 1 item

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium is maintained by ion pumps in the cell membrane. The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.

FDA Pharmacological Classification · 4 items

KALI ACETICUM

Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]; Increased Large Intestinal Motility [PE]; Potassium Salt [EPC]; Potassium Compounds [CS]; Osmotic Laxative [EPC]

POTASSIUM ACETATE

Potassium Compounds [CS]; Osmotic Laxative [EPC]; Increased Large Intestinal Motility [PE]; Potassium Salt [EPC]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]; Osmotic Activity [MoA]

Absorption, Distribution and ExcretionMostly urine but also skin and feces.

Uses & manufacturing

Uses · 3 items

CIR ingredient: Potassium Acetate

Used as a potassium supplement; [Merck Index] Used in the chemical industry (synthesis), textile processing industry, anti-freeze agents, foods (permitted additive in the UK), and pharmaceuticals; Also used as a pH regulator and industrial de-icer; [IUCLID] Used in foods as a buffer and antimicrobial preservative; [JECFA] Used as a dehydrating agent and in crystal glass; [Hawley]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry];Glass Manufacturing [Category: Industry]

U.S. Production2023: 250,000,000 - <400,000,000 lb;2022: 250,000,000 - <400,000,000 lb;2021: 250,000,000 - <400,000,000 lb;2020: 100,000,000 - <250,000,000 lb
Consumer UsesAnti-scaling agent;Not Known or Reasonably Ascertainable;Soil amendments (fertilizers);Preservative;Flame retardant;Lubricating agent;Other;Anti-freeze agent
Industry Uses · 1 item

Chemical reaction regulator;pH regulating agent;Other;Lubricating agent;Anti-freeze agent;Defoamer;Laboratory chemicals;Intermediate;Preservative;Soil amendments (fertilizers);Catalyst;Corrosion inhibitor;Not Known or Reasonably Ascertainable;Flame retardant

Household ProductsInformation on 3 consumer products that contain Potassium Acetate in the following categories is provided:;• Inside the Home
Use Classification · 5 items

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Food Additives -> ACIDITY_REGULATOR; PRESERVATIVE -> JECFA Functional Classes

Cosmetics -> Film forming

Related reactions

4,436 records

Linked notes

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