Basic information
- CAS
7080-50-4- Standard SMILES
Cc1ccc(S(=O)(=O)[N-]Cl)cc1.O.O.O.[Na+]- InChIKey
NZYOAGBNMCVQIV-UHFFFAOYSA-N- Molecular formula
- C7H13ClNNaO5S
- Average molar mass
- 281.69 g/mol
- Monoisotopic mass
- 281.01006548
Names & identifiers
- Preferred name
- chloramine-T trihydrate
- IUPAC
- sodium;chloro-(4-methylphenyl)sulfonylazanide;trihydrate
- English name
- Chloramine-T trihydrate
- Molecular formula
- C7H11ClNNaO3S
- Molecular weight
- 247.67
Names & synonyms
Chloramine-T trihydrate7080-50-4Tosylchloramide sodium trihydrateChloraseptinHydroclonazoneChlorazolMinachlorTrichlorolDisifinHalamidDTXSID60407954IU6VSV0EI
Show more names
Chloramine TrihydrateChloroamine t trihydrateSODIUM P-TOLUENESULFONCHLORAMIDE TRIHYDRATEoramine TCHLOROAMINUMChloramineTGrChloramineTGr99%amide trihydrateACS， 98.0-103.0%
N-Chloro-p-toluenesulfonamide, monosodium salt, trihydrateSodium derivative of N-chloro-p-toluenesulfonamide trihydrateDTXCID4020795Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, hydrate (1:1:3)HALAMID AQUARefChem:54771Chloramine T trihydrateMFCD00149066
Database identifiers
- CAS
7080-50-4- PubChem CID
- 517414
- DTXSID
DTXSID6040795- ChEMBL
CHEMBL1591636- UNII
- 4IU6VSV0EI
- EC Number
- 615-172-8
Properties
Computed structural properties
- Topological polar surface area
- 46.5 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 231
Experimental & physicochemical properties
Animal DrugsActive Ingredients (Chloramine-T trihydrate) -> FDA Greenbook
Physicochemical properties
- Melting point
- 167 · 167-170 °C(lit.)
- Density
- 1.43 · 1.43
- bulk density
- 540 · 540-680kg/m3
- Flash point
- 92 °C · 92 °C
- storage temp.
- 2 °C · Store at +2°C to +8°C.
- solubility
- 2 O: · H2O: passes test
- form
- Crystalline Powder
- pka
- 1 · pK1:4.54(+1) (25°C)
- color
- White to off-white
- PH
- 8 · 8-10 (50g/l, H2O, 20℃)
- Odor
- Chlorine like
- PH Range
- 8 · 8 - 10
- Water Solubility
- Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.
- Sensitive
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 0.5% (1 of 222) of reports.
Danger
H302 (99.5%): Harmful if swallowed [Warning Acute toxicity, oral]
P233, P260, P264, P264+P265, P270, P271, P273, P280, P284, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P342+P316, P363, P403, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 222 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationChloramine-T, trihydrate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesAcute Tox. 4 (99.5%)
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 2
- tsca
- Yes
- rtecs
- XT5616800
- ridadr
- UN 3263 8/PG 3
- hs_code
- 29350090
- Toxicity
- LD50 orally in Rabbit: 935 mg/kg
- risk_code
- 22-31-34-42
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS07,GHS08
- hazard_code
- C
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Substances that reduce or suppress INFLAMMATION.
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Compounds that prevent the release of inflammatory mediators from MAST CELLS.
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION).
Uses & manufacturing
Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
Applications
DescriptionChloramine-T is commercially available in the form of a trihydrate and is a stable white to pale yellow solid. Chloramine T Sodium Salt Trihydrate is a reagent for selective oxidation of methionine. It is used as an antibacterial agent; a topical antiseptic. Capable of oxidative cyclization to produce various heterocycles. Nitrene source for aziridinations and aminohydroxylations. Reactant for Preparation of factor Xa inhibitors as novel anticoagulants.
Related reactions
22 records
Compound notes
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