Basic information
- CAS
97730-95-5- Standard SMILES
N#Cc1cc2c(OCC(O)CN3CCN(C(c4ccccc4)c4ccccc4)CC3)cccc2[nH]1- InChIKey
BYBYHCOEAFHGJL-UHFFFAOYSA-N- Molecular formula
- C29H30N4O2
- Average molar mass
- 466.6 g/mol
- Monoisotopic mass
- 466.23687621
Overview
4-[3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-1H-indole-2-carbonitrile is a diarylmethane.
Names & identifiers
- Preferred name
- 4-(3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
- IUPAC
- 4-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
- English name
- SDZ-201 106 (+/-)
- Molecular formula
- C29H30N4O2
- Molecular weight
- 466.57
Names & synonyms
97730-95-5Dpi 201-106DPI-201-106SDZ-2011064-[3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-1H-indole-2-carbonitrileUI0EP1D8784-(3-(4-(DIPHENYLMETHYL)-1-PIPERAZINYL)-2-HYDROXYPROPOXY)-1H-INDOLE-2-CARBONITRILEDPI201106DPI 201106DPI--201106RefChem:9121181H-Indole-2-carbonitrile, 4-(3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-, (+-)-
Show more names
SDZ-201 106 (+/-)DPI 201-106, 10 mM in DMSOSDZ-201106 (±), (DPI-201106)(+/-)-SDZ-201106 (DPI-201106)(+-)-4-(3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1h-indole-2-c1h-indole-2-carbonitrile,4-(3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxyprop4(3-(4-DIPHENYLMETHYLPIPERAZINE-1-YL)-2-HYDROXYPROPOXY)-1H-INDOL-2-CARBONITRILE4-[3-(4-diphenylmethylpiperazin-1-yl)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
DPI-201-106, (A+-)-Racemic DPI 201-1064-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy]-1H-indole-2-carbonitrile4-{3-[4-(diphenylmethyl)piperazin-1-yl]-2-hydroxypropoxy}-1h-indole-2-carbonitrileCHEMBL314639DPI 201-106;SDZ 2011061H-Indole-2-carbonitrile, 4-[3-[4-(diphenylmethyl)-1-piperazinyl]-2-hydroxypropoxy]-4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Properties
Computed structural properties
- XLogP
- 4.5
- Topological polar surface area
- 75.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 8
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 672
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 30 mg/ml; · DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1.6 mg/ml
- form
- White solid.
- color
- White to off-white
- FDA UNII
- 0 EP1D878 · UI0EP1D878
- Hazard statements
- 402 · H402
- Precautionary statements
- 273 · P273-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Hazard statements
- H402
- Precautionary statements
- P273-P501
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Applications
UsesSDZ-201106 (+/-), (DPI-201106) is a positive inotropic and calcium sensitizing agent.
Suppliers30 total
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
Aladdin Scientific[email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
InvivoChem中国13549236410 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
Wuhan Jingkang en Biomedical Technology Co., Ltd+86-0086-13720134139 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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