CAS 365-34-4 2-(Trifluoromethyl)phenylhydrazine (HCID 520800)

Names & identifiers

Preferred name: 2-(Trifluoromethyl)phenylhydrazine
IUPAC: [2-(trifluoromethyl)phenyl]hydrazine
English name: 1-[2-(Trifluoromethyl)phenyl]hydrazine
Molecular formula: C7H7F3N2
Molecular weight: 176.14

Names & synonyms

2-(Trifluoromethyl)phenylhydrazine365-34-4[2-(trifluoromethyl)phenyl]hydrazine(2-(Trifluoromethyl)phenyl)hydrazineDTXSID70334460RefChem:462581DTXCID80285550609-255-82-TrifluoromethylphenylhydrazineMFCD00052687m-TrifluoromethylphenylhydrazineHYDRAZINE, [2-(TRIFLUOROMETHYL)PHENYL]-, HYDROCHLORIDE

Show more names

BUTTPBUTTPARK 44\57-17AKOS BBS-00006978à,à,à-trifluoro-o-tolylhydrazineα,α,α-Trifluoro-o-tolylhydrazine[o-(Trifluoromethyl)phenyl]hydrazine2-(Trifluoromethyl)phenylhydrazine98%1-phenyl-1-(trifluoromethyl)hydrazine

1-[2-(Trifluoromethyl)phenyl]hydrazineHydrazine, [2-(trifluoromethyl)phenyl]-o-trifluoromethylphenylhydrazineEnamine_002408SCHEMBL358811SCHEMBL9091929SCHEMBL9091934o-trifluoromethyl-phenylhydrazine

Database identifiers

CAS: 365-34-4
PubChem CID: 520800
DTXSID: DTXSID70334460
ChEMBL: CHEMBL1621897
EC Number: 609-255-8
Nikkaji: J308.977K

Properties

Computed structural properties

XLogP: 2.6
Topological polar surface area: 38.1 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 5
Rotatable bonds: 1
Heavy atoms: 12
Formal charge: 0
Complexity: 146

Physicochemical properties

Melting point: 55 · 55-58°C
Boiling point: 221.5 · 221.5±40.0 °C(Predicted)
Density: 1.359 · 1.359±0.06 g/cm3(Predicted)
pka: 4.34 · 4.34±0.10(Predicted)
form: crystalline solid
color: Pale brown
Water Solubility: Insoluble in water.
BRN: 641592 · 641592
InChI: 1S/C7H7F3N2/c8-7(9,10)5-3-1-2-4-6(5)12-11/h1-4,12H,11H2
InChIKey: JSWQDLBFVSTSIW-UHFFFAOYSA-N
SMILES: NNc1ccccc1C(F)(F)F
CAS DataBase Reference: 365 · 365-34-4(CAS DataBase Reference)
UNSPSC Code: 12352100 · 12352100
Symbol(GHS): 7 · GHS07,GHS06
Signal word: Warning
Hazard statements: 302 · H302-H315-H319-H335-H301-H311-H332
Precautionary statements: 280 · P280-P301+P310a-P405-P501a-P261-P305+P351+P338
target organs: Respiratory system
PPE: 95 · dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes: Xi,Xn
Risk Statements: 20 · 20/21/22-36/37/38-22
Safety Statements: 26 · 26-36/37/39-36
RIDADR: 2811 · UN2811
WGK Germany: 3 · 3
Hazard Note: Irritant
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 2928009090 · 2928009090
Storage Class: 11 · 11 - Combustible Solids
Hazard Classifications: 4 OralEye · Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
Limited Quantities: 5 kg · 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (97.8%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (97.8%)

Safety data

PPE: dust mask type N95 (US), Eyeshields, Gloves
wgk: 3
ridadr: UN2811
hs_code: 2928009090
risk_code: 20/21/22-36/37/38-22
Signal word: Warning
Symbol(GHS): GHS07,GHS06
hazard_code: Xi,Xn
hazard_note: Irritant
safety_code: 26-36/37/39-36
hazard_class: IRRITANT, IRRITANT-HARMFUL
Storage Class: 11 - Combustible Solids
target organs: Respiratory system
Hazard statements: H302-H315-H319-H335-H301-H311-H332
Limited Quantities: 5.0 kg (11 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P280-P301+P310a-P405-P501a-P261-P305+P351+P338

Chemistry & industry

Applications

Uses2-(Trifluoromethyl)phenylhydrazine is used as an intermediate in organic syntheses. It is also ued as a fine chemical intermediate, GC derivatizing agent, coupling reagent and N- protecting agent.