CAS 41365-75-7 1-Amino-3,3-diethoxypropane (HCID 521029)

Names & identifiers

Preferred name: 1-Amino-3,3-diethoxypropane
IUPAC: 3,3-diethoxypropan-1-amine
English name: 1-Amino-3,3-diethoxypropane
Molecular formula: C7H17NO2
Molecular weight: 147.22

Names & synonyms

1-Amino-3,3-diethoxypropane41365-75-7DTXSID60334535RefChem:429213DTXCID70285625627-108-63,3-diethoxypropan-1-amine3,3-Diethoxypropylamine3-Aminopropionaldehyde diethylacetalMFCD001425811-Amino-3,3-diethoxypropane (APEA)SCHEMBL366440

Show more names

APEA1-Amino-3,3-diethoxypropane,97%TIMTEC-BB SBB005781RARECHEM AL BW 01233,3-Diethoxypropylazanium3,3-DIETHOXY-1-PROPYLAMINE3,3-Diethoxy-1-propanamine

SB75432Propionaldehyde, 3-amino-, diethyl acetalCS-0098622EN300-614791-Amino-3,3-diethoxypropane, >=97%, liquid3-Aminopropionaldehyde Diethyl Acetal1-Propanamine, 3,3-diethoxy-3,3-diethoxy-1-propaneamine

Database identifiers

CAS: 41365-75-7
PubChem CID: 521029
DTXSID: DTXSID60334535
ChEBI: CHEBI:228279
EC Number: 627-108-6
Nikkaji: J254.881J

Properties

Computed structural properties

XLogP: 0.2
Topological polar surface area: 44.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 6
Heavy atoms: 10
Formal charge: 0
Complexity: 62

Physicochemical properties

Boiling point: 72 °C · 72 °C (12.0016 mmHg)
Density: 0.91 g/mL · 0.91 g/mL at 25 °C(lit.)
refractive index: 1.4233 · 1.4233-1.4253
Flash point: 78 °C · 78 °C
storage temp.: room temp
solubility: Soluble in water, alcohol, and petroleum ether.
pka: 8.92 · 8.92±0.13(Predicted)
form: liquid
color: Clear colorless to yellow
biological source: synthetic (organic)
Water Solubility: water: miscible
Sensitive: Air Sensitive
InChI: InChI=1S/C7H17NO2/c1-3-9-7(5-6-8)10-4-2/h7H,3-6,8H2,1-2H3
InChIKey: PXXMSHBZYAOHBD-UHFFFAOYSA-N
SMILES: C(N)CC(OCC)OCC
CAS DataBase Reference: 41365 · 41365-75-7(CAS DataBase Reference)
UNSPSC Code: 12352202 · 12352202
NACRES: 77 · NA.77
Symbol(GHS): 5 · GHS05
Signal word: Danger
Hazard statements: 314 · H314
Precautionary statements: 280 · P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 34 · 34
Safety Statements: 26 · 26-27-36/37/39-45
RIDADR: 3267 · UN 3267 8/PG 2
WGK Germany: 3 · 3
HazardClass: 8 · 8
PackingGroup: I
HS Code: 29221985 · 29221985
Storage Class: 8 A · 8A - Combustible corrosive hazardous materials
Hazard Classifications: 1 B · Skin Corr. 1B
Limited Quantities: 1 L · 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H302 (12.8%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (12.8%)；Skin Corr. 1B (100%)

Safety data

PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: UN 3267 8/PG 2
hs_code: 29221985
risk_code: 34
Signal word: Danger
Symbol(GHS): GHS05
hazard_code: C
safety_code: 26-27-36/37/39-45
hazard_class: 8
Storage Class: 8A - Combustible corrosive hazardous materials
packing_group: I
Hazard statements: H314
Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Hazard Classifications: Skin Corr. 1B
Precautionary statements: P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405

Chemistry & industry

Applications · 2 items

Uses1-Amino-3,3-diethoxypropane has been used:with alginate in the preparation of hydrogelin the generation of polyethylene glycol (PEG) polyethylenimine (PEI) polyplexes conjugate for transfection studies in hepatocellular carcinoma cell culturesas a component of pH-sensitive PEG derivative for lipopolyplexes formation

General Description1-Amino-3,3-diethoxypropane is an effective modulator of alginate and chitosan based hydrogels and effectively used for the delivery of bone marrow stromal cells (BMSCs) for regeneration of cartilage.