Dimethyl ammonium chloride
Basic information
- CAS
506-59-2- Standard SMILES
C[NH2+]C.[Cl-]- InChIKey
IQDGSYLLQPDQDV-UHFFFAOYSA-N- Molecular formula
- C2H8ClN
- Average molar mass
- 81.54 g/mol
- Monoisotopic mass
- 81.034527
Overview
See also: Dimethylamine, hydrochloride (preferred).
Names & identifiers
- Preferred name
- Dimethyl ammonium chloride
- IUPAC
- dimethylazanium chloride
- English name
- Dimethylamine hydrochloride
- Molecular formula
- C2H8ClN
- Molecular weight
- 81.54
Names & synonyms
dimethyl ammonium chlorideDacarbazine EP Impurity D HCl (Metformin EP Impurity F HCl)METHANAMINE HYDROCHLORIDEDMAClDIMETHYLAMINE HCLDIMETHYLAMMONIUM CHLORIDEMetformin impurity F CRSDiMethylaMine hydrochloridMetformin EP Impurity F HClJACS-506-59-2Dimethylamine hydrocImatinib EP Impurity I
Database identifiers
- CAS
506-59-2- PubChem CID
- 521289
Properties
Computed structural properties
- Topological polar surface area
- 16.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Formal charge
- 0
- Complexity
- 2.8
Physicochemical properties
- Melting point
- 170 · 170-173 °C(lit.)
- Boiling point
- 95.79 °C · 95.79°C (rough estimate)
- Density
- 0.8949 · 0.8949 (rough estimate)
- bulk density
- 500 kg/m3 · 500kg/m3
- vapor pressure
- 0.1 hPa · <0.1 hPa (25 °C)
- refractive index
- 1.4202 · 1.4202 (estimate)
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 2 O: · H2O: soluble0.5g/10 mL
- form
- Crystalline Powder or Crystals
- color
- White to off-white
- PH
- 5 · 5 (100g/l, H2O, 20℃)
- Water Solubility
- 3000 g/L · 3000 g/L (20 ºC)
- Sensitive
- Hygroscopic
- Merck
- 14 · 14,3228
- BRN
- 3589311 · 3589311
- Stability
- Stable. Incompatible with strong oxidizing agents.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 3-9
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 1
- tsca
- TSCA listed
- rtecs
- IQ0220000
- hs_code
- 29211190
- Toxicity
- LD50 in mice (g/kg): 1.21 i.v., 2.00 s.c. (Hazard); LC50 in mice (ppm): 7650 (48 hr), 4725 (14 day); in rats (ppm): 4540 (6 hr) (Steinhagen)
- risk_code
- 22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 26-36/37-37/39-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319
- REACH Registrations
- Active
- Hazard Classifications
- Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2
- Precautionary statements
- P264-P270-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Applications
DescriptionDimethylamine hydrochloride is the raw material of organic synthesis, the catalyzer of analysis as an acetylize, and the preparation of azoviolet and dimethylamine aqueous solution. Dimethylamine hydrochloride deoxidation is very capable, and corrodibility is vital, so be usually used in cleaning-type soldering flux. Preparation technology is for slowly splashing into hydrochloric acid in dimethylamine for tradition, and the speed that splashes into is no more than 15 ℃ with temperature, and pH=7-8 is limited. After the reaction finishes, activated carbon decolorizing is added, the filtrate is adjusted to pH=3-4 with hydrochloric acid, decompression is steamed water to the greatest extent, obtaining dimethylamine hydrochloride.
UsesDimethylamine hydrochloride is used as an intermediate in the manufacture of pharmaceuticals like ranitidine and metformin, tramadol and amlodipine. It is used as a precursor of atrazine. It is associated with sodium acetate and used to carry out the Willgerodt- Kindler reaction to prepare amides. Its free base reacts with carbon disulfide to get dimethyldithiocarbamate which is used in rubber vulcanization. It is involved in the synthesis of dimethyl-(1-methyl-pyrrol-2-ylmethyl)-amine by reacting with 1-methyl pyrrole and formaldehyde.
UsesDimethylamine hydrochloride is a precursor to several industrially significant compounds.
UsesAs accelerator in vulcanizing rubber, tanning, manufacture of detergent soaps, or attracting boll weevils to exterminate them. As reagent for Mg.
Preparation methods
PreparationDimethylamine hydrochloride is obtained from the salt formation of dimethylamine and hydrochloric acid.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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