Basic information
- CAS
33876-97-0- Standard SMILES
N=c1c[n+](N2CCOCC2)[n-]o1- InChIKey
FKDHHVKWGRFRTG-UHFFFAOYSA-N- Molecular formula
- C6H10N4O2
- Average molar mass
- 170.17 g/mol
- Monoisotopic mass
- 170.08037557
Overview
Linsidomine is a member of morpholines.
Names & identifiers
- Preferred name
- Linsidomine
- IUPAC
- 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine
- English name
- 3-MORPHOLINOSYDNONIMINE
- Molecular formula
- C6H10N4O2
- Molecular weight
- 170.17
Names & synonyms
Linsidomine33876-97-03-Morpholinosydnone imineLinsidominaLinsidominumsin-13-MorpholinosydnoneimineCV 6645O5U71P6VQDTXSID501026026N-morpholino sydnonimine3-Morpholino-sydnonimine
Show more names
cv6643-MorpholinosydnonmineHCl3-Morpholinosydnone imine-3-ium3-MorpholinosydnonminehydrochlorideMolsidomine EP Impurity A(linsidomine)Molsidomine Impurity 1 (Molsidomine EP Impurity A)3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine
SIN-1 morpholineCV-6643-morpholinosydonimineRefChem:153577C01DX18DTXCID4015102745-azanidyl-3-(morpholin-4-yl)-1,2,3lambda5-oxadiazol-3-ylium3-MORPHOLINOSYDNONIMINE
Database identifiers
- CAS
33876-97-0- PubChem CID
- 5219
- DTXSID
DTXSID501026026- ChEMBL
CHEMBL1189150- ChEBI
CHEBI:136004- UNII
- 5O5U71P6VQ
- Nikkaji
- J314.096B
Properties
Computed structural properties
- XLogP
- 0.6
- Topological polar surface area
- 49.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 222
Physicochemical properties
- storage temp.
- 20 °C · −20°C
- solubility
- 2 O: · H2O: >10 mg/mL
- form
- solid
- color
- off-white
- FDA UNII
- 5 O5U71P6VQ · 5O5U71P6VQ
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Drugs used to cause dilation of the blood vessels.
A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)
Applications
Uses3-Morpholinosydnonimine is a potent vasodilator that inhibits platelet aggregation and cysteine proteases.
Suppliers14 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
武汉峰耀同辉化学制品有限公司027-87466105 15377573527 · [email protected]
Hefei Hirisun Pharmatech Co., Ltd+8615056975894 · [email protected]
Mainchem Co., Ltd.+86-86-05926210733 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Hefei TNJ Chemical Industry Co.,Ltd.+86-0551-65418671 +86-189 4982 3763 · [email protected]
Additional notes
DefinitionChEBI: Linsidomine is a member of morpholines.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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