Indecainide Hydrochloride
Basic information
- CAS
73681-12-6- Standard SMILES
CC(C)NCCCC1(C(N)=O)c2ccccc2-c2ccccc21.Cl- InChIKey
NXNSCUZKMVYAJQ-UHFFFAOYSA-N- Molecular formula
- C20H25ClN2O
- Average molar mass
- 344.9 g/mol
- Monoisotopic mass
- 344.1655411
Overview
See also: Indecainide (has active moiety).
Names & identifiers
- Preferred name
- Indecainide Hydrochloride
- IUPAC
- 9-[3-(propan-2-ylamino)propyl]fluorene-9-carboxamide;hydrochloride
- English name
- Indecainid
- Molecular formula
- C20H25ClN2O
- Molecular weight
- 344.8783
Names & synonyms
Indecainide hydrochloride73681-12-6Indecainide HClDecabidLY 135837M76V0B96L59H-Fluorene-9-carboxamide, 9-(3-((1-methylethyl)amino)propyl)-, monohydrochlorideLY-135837LY-135857DTXSID60223950RefChem:58935DTXCID90146441
Show more names
9-(3-(isopropylamino)propyl)-9H-fluorene-9-carboxamide hydrochloride
IndecainidIndecainide hydrochloride [USAN]Decabid;LY 135837Indecainide (hydrochloride)9-[3-(propan-2-ylamino)propyl]fluorene-9-carboxamide;hydrochloride9-(3-(Isopropylamino)propyl)fluorene-9-carboxamide monohydrochlorideIndecainide hydrochloride (USAN)UNII-M76V0B96L5
Database identifiers
- CAS
73681-12-6- PubChem CID
- 52194
- DTXSID
DTXSID60223950- ChEMBL
CHEMBL1200341- UNII
- M76V0B96L5
Properties
Computed structural properties
- Topological polar surface area
- 55.1 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 6
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 398
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physicochemical properties
- Melting point
- 216.5 · 216.5-217°; mp 203-204°
- FDA UNII
- 76 V0B96L5 · M76V0B96L5
- Toxicity
- 50 orally · LD50 orally in male, female mice, rats: 100, 96, 103, 82 mg/kg (Sandusky, Meyers)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 orally in male, female mice, rats: 100, 96, 103, 82 mg/kg (Sandusky, Meyers)
Chemistry & industry
Applications
UsesCardiac depressant (anti-arrhythmic).
UsesIndecainide Hydrochloride is a pharmaceutical analog that is used in the treatment of cardiac antiarrhythmias.
Related reactions
1 records
Compound notes
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