HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Lactose monohydrate
LACTOSE MONOHYDRATE · LACTOSE MONO · Spray dried lactose · SUGAR MILK · LACTOSE MONOHYDRATE NF · Pharmatose DCL 14 · D-(+)-Lactose Lactose SPRAY-DRIED · LACTOSE extrapure AR
Identifiers & Physical Properties
| CAS No. | 64044-51-5 |
|---|---|
| Molecular formula | C12H22O11.H2O |
| Average molar mass | 360.31 g/mol |
| Monoisotopic mass | 360.1267762 g/mol |
| SMILES | O.OCC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O |
| InChIKey | WSVLPVUVIUVCRA-UHFFFAOYSA-N |
| PubChem CID | 522113 |
Chemical & Physical Properties
| Topological polar surface area | 191 |
|---|---|
| Hydrogen bond donors | 9 |
| Hydrogen bond acceptors | 12 |
| Rotatable bonds | 4 |
| Heavy atoms | 24 |
| Formal charge | 0 |
| Complexity | 382 |
| Melting point | ~215 °C (dec.) |
| Density | 1.525 |
| Storage conditions | room temp |
| Solubility | H2O: 0.1 g/mL, clear, colorlessSoluble in water (warm) (0.1 g/mL), and ethanol (very slightly soluble). Insoluble in chloroform, and ether. |
| Physical state | Crystalline |
| Specific gravity | 1.525 |
| Color | White |
| pH | 3.5-6.0 (25℃, 0.5M in H2O) |
| optical activity | [α]22/D +52.4°, c = 4.5 in H2O |
| λmax | λ: 260 nm Amax: 0.02λ: 280 nm Amax: 0.02 |
| Merck | 14,5343 |
| BRN | 3768231 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C12H22O11.H2O/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H21H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0./s1 |
| InChIKey | HBDJFVFTHLOSDW-XBLONOLSSA-N |
| SMILES | O.OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O |
| LogP (partition coefficient) | -3.409 (est) |
| CAS DataBase Reference | 64044-51-5(CAS DataBase Reference) |
| FDA UNII | EWQ57Q8I5X |
| NIST Chemistry Reference | Lactose monohydrate(64044-51-5) |
| EPA Substance Registry System | Lactose monohydrate (64044-51-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Hazard symbols | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36-24/25 |
| Water hazard class (WGK) | 3 |
| RTECS number | OD9625000 |
| F | 3 |
| TSCA inventory status | Yes |
| Customs code | 17021900 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| Regulatory information | Chemical: D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrateLactose monohydrate: Does not have an individual approval but may be used under an appropriate group standard |
|---|---|
| Other safety information | IMAP assessments - D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate: Human health tier I assessment |
| F | 3 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | Yes |
| RTECS number | OD9625000 |
| Customs code | 17021900 |
| Risk statements (R) | 36/37/38 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
| Safety statements (S) | 26-36-24/25 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
Applications & Uses
Description
D-Lactose monohydrate is a type of lactose. D-Lactose is composed of D-galactose and D-glucose. D-Lactose monohydrate can be used as sweetener or excipient.
Uses
mosquito-repellent
Uses
[a]22 +52.4°, c = 4.5 in H2O
Uses
D-Lactose monohydrate can be used as chromatographic adsorbent.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.