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Basic information
- CAS
65473-14-5- Standard SMILES
CN(C/C=C/c1ccccc1)Cc1cccc2ccccc12.Cl- InChIKey
OLUNPKFOFGZHRT-YGCVIUNWSA-N- Molecular formula
- C21H22ClN
- Average molar mass
- 323.9 g/mol
- Monoisotopic mass
- 323.14407738
Overview
Naftifine hydrochloride is a hydrochloride and an allylamine antifungal drug.
Names & identifiers
- Preferred name
- Naftifine Hydrochloride
- IUPAC
- (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine;hydrochloride
Names & synonyms
NAFTIFINE HYDROCHLORIDE65473-14-5Naftifine HClNaftinExoderilAW 105-843DTXSID2045496SN 105843NAFT900NSC-760068NAFT-90025UR9N9041
Show more names
DTXCID0025496(E)-N-methyl-N-(1-naphthylmethyl)-3-phenyl-2-propen-1-amine-hydrochlorideN-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochlorideRefChem:57002NaftifunginAW 105843(E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochlorideNaftifine (hydrochloride)
Database identifiers
- CAS
65473-14-5- PubChem CID
- 5281098
- DTXSID
DTXSID2045496- ChEMBL
CHEMBL1200493- ChEBI
CHEBI:7452- UNII
- 25UR9N9041
- EC Number
- 620-502-9
Properties
Computed structural propertiesFilling in
- Topological polar surface area
- 3.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 5
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 342
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 66.7% (2 of 3) of all reports.
Warning
H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]
P260, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P319, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (33.3%)
Chemistry & industry
Pharmacology
FDA Pharmacological Classification
NAFTIFINE HYDROCHLORIDE
Allylamine Antifungal [EPC]; Allylamine [CS]
MeSH Pharmacological ClassificationSubstances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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