Basic information
- CAS
118201-38-0- Standard SMILES
O=[N+]([O-])O.c1ccc2c(c1)CCCC2C1=NCCN1- InChIKey
SVQFLMKSDLCPAY-UHFFFAOYSA-N- Molecular formula
- C13H17N3O3
- Average molar mass
- 263.29 g/mol
- Monoisotopic mass
- 263.12699141
Overview
Tetrahydrozoline nitrate is an organic nitrate salt obtained by reaction of equimolar amounts of tetryzoline and nitric acid. It is used as a drug for the temporary relief of discomfort and redness of eyes due to minor eye irritations. It has a role as a sympathomimetic agent, a vasoconstrictor agent and an ophthalmology drug. It contains a tetryzoline(1+).
Names & identifiers
- Preferred name
- Tetrahydrozoline Nitrate
- IUPAC
- nitric acid;2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole
- English name
- 4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole mononitrate
- Molecular formula
- C13H17N3O3
- Molecular weight
- 263.3
Names & synonyms
Tetrahydrozoline nitrate118201-38-0Tetryzolin nitratetetryzoline nitrateNarbelTetrahydrozoline nitrate [JAN]4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole mononitrateUNII-8P9X484T3FNarbel (TN)Tetrahydrozoline nitrate (JAN)8P9X484T3F2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole nitrate
Show more names
Acedoben Impurity 10tetrahydrazoline nitrate4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazo...nitric acid,2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, mononitrate (9CI)
CHEBI:1455701H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, mononitrateTETRYZOLINE NITRATE [WHO-DD]1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, nitrate (1:1)RefChem:18872184-22-0, Tetrahydrozoline(+-)-TETRAHYDROZOLINE NITRATE(+/-)-Tetrahydrozoline nitrate
Database identifiers
- CAS
118201-38-0- PubChem CID
- 5282385
- ChEBI
CHEBI:145570- UNII
- 8P9X484T3F
Properties
Computed structural properties
- Topological polar surface area
- 90.4 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 284
Physicochemical properties
- FDA UNII
- 8 P9X484T3F · 8P9X484T3F
Chemistry & industry
Applications
UsesTetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].
Suppliers14 total
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
南兴化工（江苏）有限公司0512-66387035 18662433356 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
上海万千化工有限公司18796480002 18796480002 · [email protected]
武汉赢元贝商贸有限公司86-13349903920 13349903920 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
郑州艾克姆化工有限公司13303867194 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海亿万化工有限公司00-18662433356 18662433356 · [email protected]
武汉赢元贝商贸有限公司13349903920 · [email protected]
重庆卡兰医药有限公司[email protected]
HANGZHOU CLAP TECHNOLOGY CO.,LTD86-571-88216897,88216896 13588875226 · [email protected]
Hefei TNJ Chemical Industry Co.,Ltd.+86-0551-65418684 +86-18949823763 · [email protected]
Additional notes
DefinitionChEBI: Tetrahydrozoline nitrate is an organic nitrate salt obtained by reaction of equimolar amounts of tetryzoline and nitric acid. It is used as a drug for the temporary relief of discomfort and redness of eyes due to minor eye irritations. It has a role as a vasoconstrictor agent, an ophthalmology drug and a sympathomimetic agent. It contains a tetryzoline(1+).
Related reactions
0 records
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Compound notes
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