Basic information
- CAS
10164-73-5- Standard SMILES
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](CCCCCCC(=O)O)[C@H](O)C[C@H]1O- InChIKey
DZUXGQBLFALXCR-JQXWHSLNSA-N- Molecular formula
- C20H36O5
- Average molar mass
- 356.5 g/mol
Overview
Prostaglandin F1beta is a prostanoid.
Names & identifiers
- Preferred name
- Prostaglandin F1beta
- IUPAC
- 7-[(1R,2R,3R,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]heptanoic acid
- English name
- 9beta,11alpha,15S-trihydroxy-prost-13e-en-1-oic acid
- Molecular formula
- C20H36O5
- Molecular weight
- 356.5
Names & synonyms
PGF1betaProstaglandin F1beta10164-73-5Prostaglandin F1 beta9R,11R,15S-trihydroxy-13E-prostaenoic acidRefChem:172350prostaglandin F1beta, (9beta,11alpha,13E,15S)-7-[(1R,2R,3R,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]heptanoic acidProstaglandin F1|AProst-13-en-1-oic acid, 9,11,15-trihydroxy-, (9beta,11alpha,13E,15S)-9beta,11alpha,15S-Trihydroxy-prost-13E-en-1-oic acidProstaglandin F1.beta.
Show more names
PGF1β9BETA-PGF1ALPHAProstaglandin F1βAlprostadil ImpurityAlprostadil (prostaglandin E1) impurity 19Alprostadil (Prostaglandin E1) Impurity 12Prost-13-en-1-oic acid, 9,11,15-trihydroxy-, (9β,11α,13E,15S)-
orb2283700SCHEMBL3366182CHEBI:165335DZUXGQBLFALXCR-JQXWHSLNSA-NHMS3648L117-((1R,2R,3R,5R)-3,5-Dihydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)heptanoic acidLMFA03010069MFCD00135223
Properties
Computed structural properties
- XLogP
- 3.5
- Topological polar surface area
- 98 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 13
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 396
Experimental & physicochemical properties
LipidsFatty Acyls [FA] -> Eicosanoids [FA03] -> Prostaglandins [FA0301]
Physicochemical properties
- Boiling point
- 526.5 · 526.5±50.0 °C(Predicted)
- Density
- 1.136 · 1.136±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- 50 mg/ml; · DMF: >50 mg/ml; DMSO: >50 mg/ml; Ethanol: >75 mg/ml; PBS pH 7.2: >2 mg/ml
- form
- A crystalline solid
- pka
- 4.78 · 4.78±0.10(Predicted)
- InChI
- 1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18+,19+/m0/s1
- InChIKey
- DZUXGQBLFALXCR-JQXWHSLNSA-N
- SMILES
- O[C@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1
- UNSPSC Code
- 12352211 · 12352211
- NACRES
- 25 · NA.25
Safety & regulation
Safety data
- wgk
- WGK 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
DescriptionPGF1β is the C-9 epimer of PGF1α. It was shown to enhance respiratory rate in experimental animals when administered intravenously.1
UsesProstaglandin F1β (PGF1β) is the C-9 epimer of 1α. Prostaglandin F1β increased the respiratory rate of rabbits[1].
Suppliers9 total
湖北瑞玛标物科技有限公司15787879035 15787875101 · [email protected]
河南誉康卓宁进出口有限公司13393721940 · [email protected]
湖北摩科化学有限公司18627753421; 18627756402 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
梯尔希（南京）药物研发有限公司18012923235 · [email protected]
上海甄准生物科技有限公司18019219489 18901678489 · [email protected]
Additional notes
DefinitionChEBI: PGF1beta is a prostanoid.
Related reactions
7 records
Compound notes
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