HuagongsheHuagongshe Chemistry Print Report · For research reference only

HCID 5284447Generated: November 2, 2026

Natamycin

https://huagongshe.com/en/chemical/5284447

Identifiers & Physical Properties

CAS No.	52882-37-8
Molecular formula	C33H47O13N
Average molar mass	665.7 g/mol
Monoisotopic mass	665.30474055 g/mol
SMILES	C[C@@H]1C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3/C=C/C(=O)O1)C[C@H](O)[C@H]2C(=O)O
InChIKey	NCXMLFZGDNKEPB-FFPOYIOWSA-N
PubChem CID	5284447
ChEMBL	CHEMBL1200656
EC No.	231-683-5
DTXSID	DTXSID6021163

Chemical & Physical Properties

XLogP	-1.3
Topological polar surface area	231
Hydrogen bond donors	7
Hydrogen bond acceptors	14
Rotatable bonds	3
Heavy atoms	47
Formal charge	0
Complexity	1,220
Drugs	Pharmaceuticals -> Antibiotics
pH	5,5-7,5 (1 % w/v solution in previously neutralised mixture of 20 parts dimethylformamide and 80 parts of water)
Pesticides	Other TreatmentActive substance -> EU Pesticides database: Pending
Food additives	FUMIGANT -> FDA Substance added to food
Human Drugs	Breast FeedingLactationMilk, HumanAntibacterial AgentsAnti-Infective Agents, LocalAntifungal AgentsFDA approved drugs -> Active ingredientOphthalmological preparations > Anti-infective agents
Optical Rotation	[α]D/20 + 250° to + 295° (a 1 % w/v solution in glacial acetic acid, at 20 °C and calculated with reference to the dried material)
Physical Description	White to creamy-white crystalline powder

Safety & Regulations

GHS classification	This chemical does not meet GHS hazard criteria for 100% (6 of 6) of all reports.Not ClassifiedAggregated GHS information provided per 6 reports by companies from 1 notifications to the ECHA C&L Inventory.
Regulatory information	Directive (EC) No 2/1995 (Repealed by Reg. EC No 1333/2008 (amended))Natamycin: Does not have an individual approval but may be used under an appropriate group standard
Other safety information	IMAP assessments - Pimaricin: Environment tier I assessmentIMAP assessments - 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-: Environment tier I assessment
Hazard Classes and Categories	Not Classified
Effects During Pregnancy and Lactation	◉ Summary of Use during Lactation

Identifiers & Physical Properties

CAS No.

52882-37-8

Molecular formula

C33H47O13N

Average molar mass

665.7 g/mol

Monoisotopic mass

665.30474055 g/mol

SMILES

C[C@@H]1C/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3/C=C/C(=O)O1)C[C@H](O)[C@H]2C(=O)O

InChIKey

NCXMLFZGDNKEPB-FFPOYIOWSA-N

PubChem CID

5284447

ChEMBL

CHEMBL1200656

EC No.

231-683-5

DTXSID

DTXSID6021163

Chemical & Physical Properties

XLogP

-1.3

Topological polar surface area

231

Hydrogen bond donors

Hydrogen bond acceptors

Rotatable bonds

Heavy atoms

Formal charge

Complexity

1,220

Drugs

Pharmaceuticals -> Antibiotics

5,5-7,5 (1 % w/v solution in previously neutralised mixture of 20 parts dimethylformamide and 80 parts of water)

Pesticides

Other TreatmentActive substance -> EU Pesticides database: Pending

Food additives

FUMIGANT -> FDA Substance added to food

Human Drugs

Breast FeedingLactationMilk, HumanAntibacterial AgentsAnti-Infective Agents, LocalAntifungal AgentsFDA approved drugs -> Active ingredientOphthalmological preparations > Anti-infective agents

Optical Rotation

[α]D/20 + 250° to + 295° (a 1 % w/v solution in glacial acetic acid, at 20 °C and calculated with reference to the dried material)

Physical Description

White to creamy-white crystalline powder

Safety & Regulations

GHS classification

This chemical does not meet GHS hazard criteria for 100% (6 of 6) of all reports.Not ClassifiedAggregated GHS information provided per 6 reports by companies from 1 notifications to the ECHA C&L Inventory.

Regulatory information

Directive (EC) No 2/1995 (Repealed by Reg. EC No 1333/2008 (amended))Natamycin: Does not have an individual approval but may be used under an appropriate group standard

Other safety information

IMAP assessments - Pimaricin: Environment tier I assessmentIMAP assessments - 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-: Environment tier I assessment

Hazard Classes and Categories

Not Classified

Effects During Pregnancy and Lactation

◉ Summary of Use during Lactation