Basic information
- CAS
206193-18-2- Standard SMILES
C[C@](O)(CBr)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1- InChIKey
QDSWNDMHSBZXKX-JTQLQIEISA-N- Molecular formula
- C11H10BrF3N2O4
- Average molar mass
- 371.11 g/mol
- Monoisotopic mass
- 369.9776
Names & identifiers
- Preferred name
- (R)-3-Bromo-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
- IUPAC
- (2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
- English name
- (2R)-3-Bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
- Molecular formula
- C11H10BrF3N2O4
- Molecular weight
- 371.11
Names & synonyms
(R)-3-bromo-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDERefChem:407287206193-18-2(2R)-3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamideCHEMBL296323MFCD124057582ax9C11H10BrF3N2O4SCHEMBL1124550SCHEMBL29504174BDBM18699
Show more names
3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Propanamide, 3-bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, (2R)-AKOS015895054DB07454PD005170NS00070930Q27096673N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2R)-3-bromo-2-hydroxy-2-me thylpropanamiden-[4-nitro-3-(trifluoromethyl)phenyl]-(2r)-3-bromo-2-hydroxy-2-methylpropanamide
Database identifiers
- CAS
206193-18-2- PubChem CID
- 5287785
- ChEMBL
CHEMBL296323- Nikkaji
- J949.143K
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 95.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 3
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 415
Physicochemical properties
- Melting point
- 100 · 100-101.5 °C
- Boiling point
- 491.7 · 491.7±45.0 °C(Predicted)
- Density
- 1.753 · 1.753
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 11.68 · 11.68±0.29(Predicted)
- form
- Solid
- color
- Light Yellow
Chemistry & industry
Applications
Uses(2R)-3-Bromo-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide is an intermediate in the synthesis of 4-Desacetamido-4-fluoro Andarine (D289530), a Selective Androgen Receptor Modulator (SARM) that has potential use for treatment of androgen related diseases such as muscle wasting and osteoporosis.
Suppliers7 total
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
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济南睿思医药技术有限公司0531-0531-69900633 19963472814 · [email protected]
重庆卡兰医药有限公司[email protected]
上海语锌医药科技有限公司15921286451; 15921286451 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
Related reactions
12 records
Compound notes
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