Basic information
- CAS
75859-03-9- Standard SMILES
C[C@@H]1CN(CCCn2c3ccccc3c3ccccc32)C[C@H](C)N1.Cl.Cl- InChIKey
ZWHRZGHGYMUSRM-VWDRLOGHSA-N- Molecular formula
- C21H29Cl2N3
- Average molar mass
- 394.4 g/mol
- Monoisotopic mass
- 393.1738533
Names & identifiers
- Preferred name
- Rimcazole dihydrochloride
- IUPAC
- 9-[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]propyl]carbazole;dihydrochloride
- English name
- 9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]-9H-carbazole dihydrochloride
- Molecular formula
- C21H29Cl2N3
- Molecular weight
- 394.38
Names & synonyms
Rimcazole dihydrochlorideDTXSID20481619-[3-(CIS-3,5-DIMETHYL-1-PIPERAZINYL)PROPYL]-9H-CARBAZOLE DIHYDROCHLORIDE9-(3-(cis-3,5-Dimethyl-1-piperazinyl)propyl)-9H-carbazole dihydrochlorideRefChem:883643DTXCID801764514622-272-575859-03-9RIMCAZOLE HYDROCHLORIDEBW 234U dihydrochlorideRimcazole (dihydrochloride)Rimcazole hydrochloride [USAN]
Show more names
Rimcazolebw234uRimcazole2HClReaxys ID: 57852359-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole dihydrochloridecis-9-(3-(3,5-dimethyl-1-piperazinyl)propyl)-9h-carbazoledihydrochloride9-(3-(3,5-dimethyl-l-piperazinyl)propyl)-,dihydrochloride,cis-9h-carbazol
9-(3-(cis-3,5-Dimethylpiperazin-1-yl)propyl)-9H-carbazole dihydrochlorideBW-234U Dihydrochloride2XAC11FCQ49-[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]propyl]carbazole;dihydrochlorideRimcazole hydrochloride (USAN)DTXCID7025681Rimcazole HClCAS-75859-03-9
Database identifiers
Properties
Computed structural properties
- Topological polar surface area
- 20.2 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 4
- Heavy atoms
- 26
- Formal charge
- 0
- Complexity
- 380
Physicochemical properties
- storage temp.
- 4 °C · Store at +4°C
- form
- Powder
- color
- White to off-white
- Water Solubility
- 10 mM · Soluble to 10 mM in water
- FDA UNII
- 2 XAC11FCQ4 · 2XAC11FCQ4
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H302-H335
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H302-H335
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
UsesRimcazole Dihydrochloride is a small molecule antagonist of the σ-1 receptor and inhibits tumor cell survival.
Suppliers20 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
上海瀚香生物科技有限公司177-54423994 17754423994 · [email protected]
湖北魏氏化学试剂股份有限公司17771898297 13125137661 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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