Basic information
- CAS
82989-25-1- Standard SMILES
CCCCOC(=O)C(=O)Nc1cccc(-c2nn[nH]n2)c1- InChIKey
XQTARQNQIVVBRX-UHFFFAOYSA-N- Molecular formula
- C13H15N5O3
- Average molar mass
- 289.29 g/mol
- Monoisotopic mass
- 289.11748936
Overview
Tazanolast is an organic molecular entity.
Names & identifiers
- Preferred name
- Butyl 2-oxo-2-((3-(2H-tetrazol-5-yl)phenyl)amino)acetate
- IUPAC
- butyl 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetate
- English name
- Tazanolast
- Molecular formula
- C13H15N5O3
- Molecular weight
- 289.29
Names & synonyms
tazanolast82989-25-1TazanolTazanolastumDTXSID6048626Butyl 3'-(1H-tetrazol-5-yl)oxanilateDTXCID3028552T0248823H1RefChem:917750butyl-3'-(1H-tetrazol-5-yl)oxanilateButyl 2-oxo-2-((3-(2H-tetrazol-5-yl)phenyl)amino)acetatebutyl 2-oxo-2-[3-(2H-tetrazol-5-yl)anilino]acetate
Show more names
TO-188Tazanolast(Tazalest,TO 188,WP 833)Butyl 3'-(1H-tetrazol-5-y1)oxanilateN-[3-(1H-Tetrazol-5-yl)phenyl]oxamidic acid butyl ester
WP-8335-(3-n-Butyloxalylaminophenyl)tetrazoleTO 188; Tazalest; TazanolCHEMBL564109NCGC00183655-01TazalestTazanolast [INN:JAN]Butyl 2-((3-(1H-tetrazol-5-yl)phenyl)amino)-2-oxoacetate
Database identifiers
- CAS
82989-25-1- PubChem CID
- 5380
- DTXSID
DTXSID6048626- ChEMBL
CHEMBL564109
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 110 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 7
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 366
Physicochemical properties
- Density
- 1.343 · 1.343
- storage temp.
- 2 · 2-8°C
- solubility
- Soluble in DMSO
- pka
- 4.06 · 4.06±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- FDA UNII
- 248823 H1 · T0248823H1
Chemistry & industry
Applications
DescriptionTazanolast is an orally active antiallergic agent useful in the treatment of bronchial asthma and nasal allergy. Mechanistically it appears to inhibit IgG and IgE-mediated antigen-antibody reactions.
UsesTAZANOLAST is used for bronchial asthma.
Upstream & downstream products
Upstream raw materials
Suppliers15 total
LGM Pharma1-(800)-881-8210 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
武汉凯美克化学科技有限公司027-87342388 18086026008 · [email protected]
武汉鹏胤药业有限公司13163333255 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
苏州爱玛特生物科技有限公司0512-56316828 400-867-5858;400-867-5858 · [email protected]
Related reactions
2 records
Compound notes
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