Tetraethylammonium

HCID 5413
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Basic information

CAS
1185-59-7
Standard SMILES
CC[N+](CC)(CC)CC
InChIKey
CBXCPBUEXACCNR-UHFFFAOYSA-N
Molecular formula
C8H20N+
Average molar mass
130.25 g/mol
Monoisotopic mass
130.15902606

Overview

Tetraethylammonium is a quaternary ammonium ion.

Names & identifiers

Preferred name
Tetraethylammonium
IUPAC
tetraethylazanium
English name
Tetraethylammonium acetate
Molecular formula
C10H23NO2
Molecular weight
189.3

Names & synonyms

TetraethylammoniumtetraethylazaniumTetramonN,N,N-TriethylethanaminiumTetrylammonium66-40-0TETRAETHYLAMMONIUM IONAMMONIUM, TETRAETHYL-Ethanaminium, N,N,N-triethyl-5AV7G7EIEETetraethylammonium cationNSC-156315
Show more names
[E4N]AcNsc152122TetraethylammoniumacetatTetraethylaminium·acetateTetraethylazanium acetateTETRAETHYLAMMONIUM ACETATEtetraethylammomium acetateAmmonium, tetraethyl-, acetateTetraethylammonium acetate，99%Tetraethylammonium acetate ,98%
NSC-102778DTXSID2045024CHEBI:44296Ion, TetraethylammoniumRefChem:896989DTXCID0025024TetraetilammonioTetraetilammonio [Italian]

Database identifiers

CAS
1185-59-7、66-40-0
PubChem CID
5413
DTXSID
DTXSID2045024
ChEMBL
CHEMBL9324
ChEBI
CHEBI:44296
UNII
5AV7G7EIEE
Nikkaji
J91.253K

Properties

Computed structural properties

XLogP
1.7
Topological polar surface area
0 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
0
Rotatable bonds
4
Heavy atoms
9

Experimental & physicochemical properties

PFASPFAS -> Other/unspecified
DrugsPharmaceuticals -> Listed in ZINC15
SolubilitySoluble in water.
Ionization Efficiency · 6 items

Positive

3.95

2.7

Agilent XCT

Electrospray ionization

formic acid (5.3nM)

Collision Cross Section125.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9044457]

Physicochemical properties

Melting point
42 · 42-46 °C(lit.)
storage temp.
2 · Sealed in dry,2-8°C
CAS DataBase Reference
1185 · 1185-59-7(CAS DataBase Reference)
FDA UNII
97 WT7282 · JX97WT7282
EPA Substance Registry System
Ethanaminium, N,N,N-triethyl-, acetate (1185-59-7)
Symbol(GHS)
7 · GHS07

Safety & regulation

Safety data

wgk
3
tsca
TSCA listed
ridadr
UN 1325 4.1/PG 2
risk_code
11
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Pharmacology

PharmacodynamicsTetraethylammonium is a vasodilator because it blocks autonomic ganglia and prevents signals carrying vasoconstrictor impulses from proceeding.
Mechanism of ActionTetraethylammonium's mechanism of action is still being investigated, but it is known that it blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors.
MeSH Pharmacological ClassificationA class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
Absorption, Distribution and ExcretionTetraethylammonium is eliminated by active renal tubular secretion by the cation transport system.

Applications

UsesTetraethylammonium Acetate is a catalyst used to prepare carbon dioxide-cyclohexene epoxide alternating copolymer with catalyst aluminum complex-ammonium salt system.

Suppliers81 total

江西益众化工有限公司15307925109 15350027073 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]

Related reactions

117 records
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Compound notes

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