Basic information
- CAS
13464-58-9- Standard SMILES
O[As](O)O- InChIKey
GCPXMJHSNVMWNM-UHFFFAOYSA-N- Molecular formula
- AsH3O3
- Average molar mass
- 125.944 g/mol
- Monoisotopic mass
- 125.929814
Overview
Arsenous acid is an arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom. It is a conjugate acid of an arsenite(1-).
Names & identifiers
- Preferred name
- Arsenous acid
- IUPAC
- arsorous acid
- English name
- arsenous acid
- Molecular formula
- AsH3O3
- Molecular weight
- 125.94
Names & synonyms
Arsenous acidarsorous acidTRIHYDROXYARSENITE(III)13464-58-9arsenic trihydroxideH3AsO3As(OH)3935XD1L5K2DTXSID7074828CHEBI:49900RefChem:114198DTXCID3034240
Show more names
Arsenous acid (9CI)Arsenous acid (as As)GCPXMJHSNVMWNM-UHFFFAOYSA-NCarbon Dioxide in Nitrogen (Nominal Amount-of-Substance Fraction 500 μmol/mol)
arsenous trioxidediarsonic trioxidearsenic (III) trioxideArsenious acid (H3AsO3)UNII-935XD1L5K2Arsenic (white)trioxoarsenic acidtrihydroxidoarsenic
Database identifiers
- CAS
13464-58-9、15502-74-6- PubChem CID
- 545
- DTXSID
DTXSID7074828- ChEMBL
CHEMBL1236189- ChEBI
CHEBI:49900- UNII
- 935XD1L5K2
- Nikkaji
- J43.679H
Properties
Computed structural properties
- Topological polar surface area
- 60.7 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 4
- Formal charge
- 0
- Complexity
- 8
Experimental & physicochemical properties
Chemical ClassesMetals -> Arsenic Compounds, Inorganic
Boiling Point465 °C
Physical Description
Solid
V (@25 °C)
Physicochemical properties
- form
- exists only in solution
- pka
- 6.86 · 6.86±0.53(Predicted)
- color
- exists only in solution
- FDA UNII
- 935 XD1L5K2 · 935XD1L5K2
- EPA Substance Registry System
- Arsenous acid (13464-58-9)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Hazards SummarySee Arsenic and the linked occupational diseases.
Safety & protection
Exposure Control and Personal ProtectionBiological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;
Minimum Risk LevelAcute Oral: 0.005 mg/kg/day (L134)
Chronic Oral: 0.0003 mg/kg/day (L134)
Chronic Inhalation: 0.01 mg/m3 (L134)
Threshold Limit Values (TLV)0.01 [mg/m3], as As
Permissible Exposure Limit (PEL)0.01 [mg/m3], as As
Protective Action Criteria (PAC)
0.050 [mg/m3]
0.78 [mg/m3]
4.7 [mg/m3]
Immediately Dangerous to Life or Health (IDLH)5.0 [mg/m3], as As
Toxicology
Treatment
Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)
Uses & manufacturing
Uses
Arsenic and its compounds are used in pesticides, wood preservatives, paints/pigments, and various metal alloys (electronics). Small amounts of arensic can be found in contaminated air, water, and some meat products, especially seafood. (L2)
Applications
UsesPesticides.
Upstream & downstream products
Downstream products
Suppliers1 total
斯派螺（武汉）药物研发有限公司[email protected]
Additional notes
DefinitionChEBI: Arsenous acid is an arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom. It is a conjugate acid of an arsenite(1-).
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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