Basic information
- CAS
85136-71-6- Standard SMILES
Cn1cc(OCC(O)CNC(C)(C)C)c2ccccc2c1=O- InChIKey
TWVUMMQUXMYOOH-UHFFFAOYSA-N- Molecular formula
- C17H24N2O3
- Average molar mass
- 304.4 g/mol
- Monoisotopic mass
- 304.17869263
Overview
Tilisolol is a member of isoquinolines.
Names & identifiers
- Preferred name
- Tilisolol
- IUPAC
- 4-[3-(tert-butylamino)-2-hydroxypropoxy]-2-methylisoquinolin-1-one
- English name
- Tilisolol
- Molecular formula
- C17H24N2O3
- Molecular weight
- 304.38
Names & synonyms
Tilisolol85136-71-6TilisololumQUF41MF56GDTXSID00438464-(3(tert-butylamino)-2-hydroxypropoxy)-N-methylisocarbostyril1(2H)-Isoquinolinone, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-2-methyl-RefChem:190015DTXCID8023846Tilisolol [INN]4-[3-(tert-butylamino)-2-hydroxypropoxy]-2-methylisoquinolin-1-oneTilisolol (INN)
Show more names
Tilisolol USP/EP/BP4-(3-tert-Butylamino-2-hydroxypropoxy)-2-methylisoquinoline-1(2H)-one(+-)-4-(3-tert-Butylamino-2-hydroxypropoxy)-2-methyl-1(2H)-isoquinolinone4-(3-tert-Butylamino-2-hydroxypropoxy)-2-methyl-1,2-dihydroisoquinoline-1-one4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropyloxy]-2-methylisoquinolin-1(2H)-one1(2H)-Isoquinolinone, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-2-methyl-1(2H)-Isoquinolinone, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-2-methyl- (9CI)
Tilisololum [Latin]UNII-QUF41MF56GTILISOLOL [MI]4-(3-tert-Butylamino-2-hydroxypropoxy)-2-methyl-1-isoquinolinoneTILISOLOL [WHO-DD]SCHEMBL49651CHEMBL1742457CHEBI:135291
Database identifiers
- CAS
85136-71-6- PubChem CID
- 5474
- DTXSID
DTXSID0043846- ChEMBL
CHEMBL1742457- ChEBI
CHEBI:135291- UNII
- QUF41MF56G
- Nikkaji
- J372.135C
Properties
Computed structural properties
- XLogP
- 1.1
- Topological polar surface area
- 61.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 6
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 428
Physicochemical properties
- FDA UNII
- 41 MF56G · QUF41MF56G
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
Applications
UsesTilisolol is an antihypertensive medication. A beta-blocker used for the treatment of angina pectoris.
Upstream & downstream products
Upstream raw materials
Suppliers4 total
Sinoway Industrial co., ltd.+86-0592-5800732 +86-13806035118 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
HBCChem, Inc.+1-510-219-6317 · [email protected]
Dideu Industries Group Limited+86-29-81148696 +86-15129568250 · [email protected]
Additional notes
DefinitionChEBI: Tilisolol is a member of isoquinolines.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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