6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione
Basic information
- CAS
154164-30-4- Standard SMILES
Cl.O=c1[nH]c2cc(-n3ccnc3)c([N+](=O)[O-])cc2[nH]c1=O- InChIKey
UMLFDVOHVJPDIZ-UHFFFAOYSA-N- Molecular formula
- C11H8ClN5O4
- Average molar mass
- 309.66 g/mol
- Monoisotopic mass
- 309.0264814
Overview
inhibits AMPA receptor binding; structure given in first source
Names & identifiers
- Preferred name
- 6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione
- IUPAC
- 6-imidazol-1-yl-7-nitro-1,4-dihydroquinoxaline-2,3-dione;hydrochloride
- English name
- YM90Khydrochloride
- Molecular formula
- C11H7N5O4.HCl
- Molecular weight
- 0
Names & synonyms
154164-30-4YM90KUAEXCLWI0QYM-90K6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione2,3-Quinoxalinedione, 1,4-dihydro-6-(1H-imidazol-1-yl)-7-nitro-, monohydrochlorideDTXSID00165547RefChem:103969DTXCID6088038YM 90K hydrochlorideYM90K hydrochlorideYM-90K hydrochloride
Show more names
CS-885YM 90K6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-1,4-Dihydro-6-(1H-imidazol-1-yl)-7-nitro-2,3-quinoxalinedionehydrochloride2,3-Quinoxalinedione,1,4-dihydro-6-(1H-imidazol-1-yl)-7-nitro-,monohydrochloride2,3-Quinoxalinedione,1,4-dihydro-6-(1H-imidazol-1-yl)-7-nitro-, hydrochloride (1:1)
YM90KHYDROCHLORIDEUNII-UAEXCLWI0Qym 9006-(1h-imidazol-1-yl)-7-nitro-2,3(1h,4h)-quinoxalinedione hydrochloride1,4-Dihydro-6-(1H-imidazol-1-yl)-7-nitro-2,3-quinoxalinedione monohydrochloride6-imidazol-1-yl-7-nitro-1,4-dihydroquinoxaline-2,3-dione;hydrochloride6-(1H-Imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione monohydrochlorideYM-90K HCl
Properties
Computed structural properties
- Topological polar surface area
- 122 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 451
Physicochemical properties
- storage temp.
- Desiccate at RT
- solubility
- 10 mM · Soluble to 10 mM in DMSO with gentle warming
- form
- Powder
- color
- Yellow to brown
- FDA UNII
- 0 Q · UAEXCLWI0Q
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used to prevent SEIZURES or reduce their severity.
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
Applications
UsesYM 90K Hydrochloride is a selective AMPA receptor antagonist.
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Compound notes
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