Basic information
- CAS
1197-17-7- Standard SMILES
NCC1CCC(C(=O)O)CC1- InChIKey
GYDJEQRTZSCIOI-UHFFFAOYSA-N- Molecular formula
- C8H15NO2
- Average molar mass
- 157.21 g/mol
- Monoisotopic mass
- 157.11027872
Overview
Tranexamic acid is a monocarboxylic acid. It has a role as an antifibrinolytic drug and a hematologic agent. It is functionally related to a cyclohexanecarboxylic acid.
Names & identifiers
- Preferred name
- 4-(Aminomethyl)cyclohexanecarboxylic acid
- IUPAC
- 4-(aminomethyl)cyclohexane-1-carboxylic acid
- English name
- cis-4-aminomethylcyclohexane-1-carboxylic acid
- Molecular formula
- C8H15NO2
- Molecular weight
- 157.21
Names & synonyms
701-54-24-(Aminomethyl)cyclohexanecarboxylic acidCyclohexanecarboxylic acid, 4-(aminomethyl)-4-(Aminomethyl)-Cyclohexanecarboxylic AcidDTXSID50904827RefChem:1070026DTXCID1025350622-133-9tranexamic acid1197-18-81197-17-7trans-4-(Aminomethyl)cyclohexanecarboxylic acid
Show more names
(1s,4s)-4-(aminomethyl)cyclohexane-1-carboxylic acidTranexamic EP Impurity Bcis-AMCHAcis-TranexaMic AcidTranexamic EP Imp BTranexamic EP Impurity 1Tranexamic Acid EP Impurity BTranexamic Acid EP Impurity B Acis-4-(Aminomethyl)-1-cyclohexanecarb4-(aminomethyl)cyclohexanecarboxylicaci
CyklokapronTrans AMCHACyclocapronTransaminAmstatTranhexamic acidTranexamsaeureRikavarin
Database identifiers
- CAS
1197-17-7、1197-18-8、701-54-2- PubChem CID
- 5526
- DTXSID
DTXSID50904827- ChEMBL
CHEMBL292500- ChEBI
CHEBI:48669- UNII
- 37YD696II6、6T84R30KC1
- EC Number
- 622-133-9
- Nikkaji
- J1.237.845I、J3.664A、J52.956G
Properties
Computed structural properties
- XLogP
- -2
- Topological polar surface area
- 63.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 139
Experimental & physicochemical properties
Drugs
Pharmaceuticals -> Listed in ZINC15
Pharmaceuticals -> Used in Switzerland
CosmeticsAstringent
Animal DrugsPharmaceuticals -> Animal Drugs -> Approved in Taiwan
Physicochemical properties
- Melting point
- 226 · 226-228°C
- Boiling point
- 300.2 · 300.2±15.0 °C(Predicted)
- Density
- 1.095 · 1.095
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Methanol (Slightly, Heated), Water (Slightly)
- form
- Solid
- pka
- 4.79 · 4.79±0.25(Predicted)
- color
- White to Light Beige
- InChI
- InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7+
- InChIKey
- GYDJEQRTZSCIOI-KNVOCYPGSA-N
- SMILES
- [C@@H]1(C(O)=O)CC[C@H](CN)CC1
- FDA UNII
- 37 YD696II6 · 37YD696II6
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-37/39
Safety & regulation
GHS classification
GHS Classification
Warning
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesEye Irrit. 2 (100%)
Safety data
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 26-37/39
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Pharmacology
ATC CodeB02AA02
Uses & manufacturing
Use Classification
Cosmetics -> Astringent
Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
Applications
Usescis-Tranexamic Acid (Tranexamic EP Impurity B) is antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.
UsesLabelled cis-Tranexamic Acid
Suppliers88 total
陕西科贝莱药物研发有限公司13119135307 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
上海策嵘生物科技有限公司[email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
Compound Net Biotechnology Inc.15266686121 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Guangzhou Tosun Pharmaceutical Limited+86-18124244216 +86-18124244216 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
广东元丰化学试剂有限公司0751-2829979 13318593351 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
海济医药科技（苏州）有限公司18012778619 · [email protected]
砌块化学科技（上海）有限公司021-20432219 13918097649 · [email protected]
上海相辉医药科技有限公司13761987713; 13761987713 · [email protected]
山东沃德森生物科技有限公司0531-88723173 18596073690 · [email protected]
济南德迈医药科技有限公司18669728830 15806766175 · [email protected]
湖北魏氏化学试剂股份有限公司17771898297 13125137661 · [email protected]
佛山宝诺生物科技有限公司0757-85921206 18520245316 · [email protected]
Moxin Chemicals+86-17320513646 +86-17320513646 · [email protected]
杭州云易国科生物科技有限公司18457506494 · [email protected]
苏州爱玛特生物科技有限公司0512-56316828 4008675858 · [email protected]
江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
泰州市众致生物科技有限公司[email protected] 15066129350 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
扬州瑞宏生物科技有限公司15380367604; 15380367604 · [email protected]
深圳菲斯生物科技有限公司0755-83725350 13380397412 · [email protected]
上海毕得医药科技股份有限公司400-164-7117 18317119277 · [email protected]
深圳摩科生化科技有限公司18627923403 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
南京熙泽医药科技有限公司025-66023220 15250997978 · [email protected]
珠海安哲生物科技有限公司13169972583 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
深圳卓越生物医药科技有限公司0755-26050679 18318671572 · [email protected]
Standardpharm Co. Ltd.86-714-3992388 · [email protected]
sgtlifesciences pvt ltd+91-8790379245 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
南京药石科技股份有限公司4000255188 · [email protected]
南京博米尔生物科技有限公司025-83453382-8005 · [email protected]
上海超岚化工科技中心（原上海巢莱）0-2022843681 15618226720 · [email protected]
湖北摩科生物科技有限公司18576690171 · [email protected]
上海平果医药科技有限公司021-20432229 · [email protected]
深圳市祥根生物医药有限公司0755-28967200 13631290199 · [email protected]
Additional notes
DefinitionChEBI: Tranexamic acid is a monocarboxylic acid. It has a role as an antifibrinolytic drug and a hematologic agent. It is functionally related to a cyclohexanecarboxylic acid.
Related reactions
36 records
Compound notes
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