Basic information
- CAS
84490-12-0- Standard SMILES
CCc1[nH]c(=O)[nH]c1C(=O)c1ccncc1- InChIKey
OQGWJZOWLHWFME-UHFFFAOYSA-N- Molecular formula
- C11H11N3O2
- Average molar mass
- 217.22 g/mol
- Monoisotopic mass
- 217.0851266
Overview
Piroximone is an organic molecular entity.
Names & identifiers
- Preferred name
- Piroximone
- IUPAC
- 4-ethyl-5-(pyridine-4-carbonyl)-1,3-dihydroimidazol-2-one
- English name
- Piroximone
- Molecular formula
- C11H11N3O2
- Molecular weight
- 217.22
Names & synonyms
Piroximone84490-12-0MDL-19205MDL 19,2052VSD0380YBDTXSID20233479MDL-19,2054-ethyl-1,3-dihydro-5-(4-pyridinylcarbonyl)-2H-imidazol-2-oneRefChem:174569DTXCID701559704-Ethyl-5-(pyridine-4-carbonyl)-1,3-dihydro-imidazol-2-oneMDL 19205
Show more names
4-Ethyl-1,3-dihydro-5-[(pyridin-4-yl)carbonyl]-2H-imidazol-2-one
Piroximona4-ethyl-5-(pyridine-4-carbonyl)-1,3-dihydroimidazol-2-one4-Ethyl-5-isonicotinoyl-4-imidazolin-2-onePiroximone (USAN)Piroximonum2H-Imidazol-2-one, 4-ethyl-1,3-dihydro-5-(4-pyridinylcarbonyl)-4-ethyl-5-(pyridine-4-carbonyl)-2,3-dihydro-1H-imidazol-2-onePIROXIMONE [USAN]
Database identifiers
- CAS
84490-12-0- PubChem CID
- 55263
- DTXSID
DTXSID20233479- ChEMBL
CHEMBL58355- ChEBI
CHEBI:230602- UNII
- 2VSD0380YB
- Nikkaji
- J22.995D
Properties
Computed structural properties
- XLogP
- 0.4
- Topological polar surface area
- 71.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 343
Experimental & physicochemical properties
LogP0.08
Physicochemical properties
- Melting point
- 264 · 264-266 °C (decomp)
- Density
- 1.245 · 1.245±0.06 g/cm3(Predicted)
- pka
- 9.86 · 9.86±0.70(Predicted)
- FDA UNII
- 2 VSD0380YB · 2VSD0380YB
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Applications
UsesCardiotonic.
Suppliers4 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
常州辰鸿生物科技有限公司+86-0519-85788828 +86-13775037613 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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