Priralfinamide

HCID 5745207
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Basic information

CAS
133865-88-0
Standard SMILES
C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
InChIKey
BHJIBOFHEFDSAU-LBPRGKRZSA-N
Molecular formula
C17H19FN2O2
Average molar mass
302.34 g/mol
Monoisotopic mass
302.14305607

Overview

Sodium Channel Blocker; structure in first source

Names & identifiers

Preferred name
Priralfinamide
IUPAC
(2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamide
English name
(2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamide
Molecular formula
C17H19FN2O2
Molecular weight
302.34

Names & synonyms

Ralfinamide133865-88-0PriralfinamideNW-1029priralfinamida(2S)-2-(4-(2-Fluorobenzyloxy)benzylamino)propanamide3LPF0S0GVVNW1029PNU-0154339EDTXSID70158406priralfinamidumRefChem:176026
Show more names
Safinamide-6Unii-3lpf0S0gvvRalfinamide [inn]Guadecitabine Sodium2- Fluoro Safinamide
DTXCID3080897(2S)-2-(((4-((2-fluorophenyl)methoxy)phenyl)methyl)amino)propanamide(S)-2-((4-((2-Fluorobenzyl)oxy)benzyl)amino)propanamide(2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamidePriralfinamide [INN]MFCD08272558RalfinamidaFCE-26742A

Database identifiers

CAS
133865-88-0
PubChem CID
5745207
DTXSID
DTXSID70158406
ChEMBL
CHEMBL2107771
UNII
3LPF0S0GVV
EC Number
603-771-7
Nikkaji
J921.657J

Properties

Computed structural properties

XLogP
2.2
Topological polar surface area
64.4 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
4
Rotatable bonds
7
Heavy atoms
22

Experimental & physicochemical properties

DrugsPharmaceuticals -> Listed in ZINC15

Physicochemical properties

Boiling point
479 · 479.0±40.0 °C(Predicted)
Density
1.189 · 1.189
storage temp.
2 · 2-8°C(protect from light)
solubility
125 mg/mL · DMSO: ≥ 125 mg/mL (413.44 mM)
pka
16.03 · 16.03±0.50(Predicted)
form
Solid

Safety & regulation

Safety data

Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H302-H315-H319-H335
Precautionary statements
P261-P305+P351+P338

Chemistry & industry

Applications

UsesRalfinamide (FCE-26742A) is an orally available Na+ blocker derived from α-aminoamide, with function of suppressing pain[1][2].

Suppliers71 total

天津始加生物医药科技有限公司15022261580 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]

Related reactions

6 records
New reaction record

Compound notes

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