Basic information
- CAS
99705-65-4- Standard SMILES
CCCN1CCO[C@@H]2c3cc(O)ccc3CC[C@H]21.Cl- InChIKey
NNEACMQMRLNNIL-CTHHTMFSSA-N- Molecular formula
- C15H22ClNO2
- Average molar mass
- 283.79 g/mol
- Monoisotopic mass
- 283.1339066
Overview
Naxagolide hydrochloride is the hydrochloride salt of naxagolide. It has a role as an anticonvulsant, an antiparkinson drug and a dopamine agonist. It contains a naxagolide(1+).
Names & identifiers
- Preferred name
- Naxagolide Hydrochloride
- IUPAC
- (4aR,10bR)-4-propyl-2,3,4a,5,6,10b-hexahydrobenzo[h][1,4]benzoxazin-9-ol;hydrochloride
- English name
- MK 458
- Molecular formula
- C15H21NO2.ClH
- Molecular weight
- 283.797
Names & synonyms
NAXAGOLIDE HYDROCHLORIDE99705-65-4Naxagolide HClMK-458MK 458E5KFJ9796WL-647,339L-647339CHEBI:177381DTXSID602442212H-Naphth(1,2-b)-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, hydrochloride, (4aR-trans)-RefChem:164888
Show more names
L 647L 647339(-)-PHNOR(+)-PHNOR-(+)-PHNONazagolide HCl
DTXCID60166712100935-99-7(+)-PHNO Hydrochlorideent Naxagolide Hydrochloride(4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol hydrochlorideNaxagolide hydrochloride [USAN]Naxagolide (hydrochloride)L 647,339
Database identifiers
- CAS
99705-65-4- PubChem CID
- 57532
- DTXSID
DTXSID60244221- ChEMBL
CHEMBL2106804- ChEBI
CHEBI:177381- UNII
- E5KFJ9796W
Properties
Computed structural properties
- Topological polar surface area
- 32.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 284
Physicochemical properties
- Melting point
- 273 · 273-275°C (dec.)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Off-White to Pale Orange
- FDA UNII
- 5 KFJ9796W · E5KFJ9796W
Chemistry & industry
Applications
UsesMK 458 is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug
UsesA dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.
Suppliers10 total
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Additional notes
ChEBI: Naxagolide hydrochloride is the hydrochloride salt of naxagolide. It has a role as an anticonvulsant, an antiparkinson drug and a dopamine agonist. It contains a naxagolide(1+).
Related reactions
0 records
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Compound notes
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