Basic information
- CAS
51-30-9- Standard SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1.Cl- InChIKey
IROWCYIEJAOFOW-UHFFFAOYSA-N- Molecular formula
- C11H17NO3.ClH
- Average molar mass
- 247.72 g/mol
- Monoisotopic mass
- 247.0975211
Overview
Isoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)
Names & identifiers
- Preferred name
- (+-)-Isoproterenol hydrochloride
- IUPAC
- 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride
- English name
- Isoproterenol hydrochloride
- Molecular formula
- C11H18ClNO3
- Molecular weight
- 247.72
Names & synonyms
Isoprenaline hydrochloride51-30-9ISOPROTERENOL HYDROCHLORIDEAeroloneAerotrolVapo-IsoIsoproterenol HClAsthpulNorisodrine AerotrolDL-Isoproterenol hydrochloridedl-Isadrine hydrochlorideIsopropylarterenol hydrochloride
Show more names
ISOPRENALINE HCLTIMTEC-BB SBB003172dl-isadrinehydrochloridedl-isoprenalinehydrochloride-n-isopropyl-dl-noradrenalineHCl
Isoprenaline chlorideMistarelSuscardiaIsovon(+-)-Isoproterenol hydrochlorideIsoproterenol monohydrochloride(+-)-Isoprenaline hydrochlorideNCI-C55630
Database identifiers
- CAS
51-30-9、949-36-0- PubChem CID
- 5807
- DTXSID
DTXSID6025486- ChEMBL
CHEMBL1711- ChEBI
CHEBI:31453- UNII
- DIA2A74855
Properties
Computed structural properties
- Topological polar surface area
- 72.7 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 187
Experimental & physicochemical properties
Solubility
Soluble (NTP, 1992)
>37.2 [ug/mL] (The mean of the results at pH 7.4)
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Melting Point338 to 340 °F (NTP, 1992)
Physical DescriptionIsoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)
Physicochemical properties
- Melting point
- 165 · 165-175 °C (dec.)(lit.)
- CAS DataBase Reference
- 949 · 949-36-0(CAS DataBase Reference)
- FDA UNII
- 2 A74855 · DIA2A74855
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36
- WGK Germany
- 2 · 2
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Other Safety InformationIMAP assessments - 1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride: Human health tier I assessment
Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Health Hazards
SYMPTOMS: Symptoms of exposure to this compound may include tremors, nervous apprehension, palpitations of the heart, epigastric distress, cardiac arrhythmias, myocardial necrosis, cardiac arrest, tachycardia, headache, flushing of the skin, anginal pain, nausea, dizziness, weakness, and sweating. (NTP, 1992)
Reactive GroupAlcohols and Polyols
Reactivity Profile
An acid organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Chemistry & industry
Pharmacology
FDA Pharmacological Classification
ISOPROTERENOL HYDROCHLORIDE
Adrenergic beta-Agonists [MoA]; beta-Adrenergic Agonist [EPC]
MeSH Pharmacological Classification
Drugs that selectively bind to and activate beta-adrenergic receptors.
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Suppliers8 total
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
南京世洲生物科技有限公司13675144456 · [email protected]
Chongqing jooe co., ltd+86-15223382610 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
金锦乐(湖南)化学有限公司18001959627(微信同号) 18001959627 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
Related reactions
5 records
Compound notes
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