Basic information
- CAS
52-62-0- Standard SMILES
C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.O=C([O-])[C@H](O)[C@@H](O)C(=O)O.O=C([O-])[C@H](O)[C@@H](O)C(=O)O- InChIKey
HSMKTIKKPMTUQH-WBPXWQEISA-L- Molecular formula
- C23H42N2O12
- Average molar mass
- 538.6 g/mol
- Monoisotopic mass
- 538.27377478
Overview
Pentolinium tartrate is the bitartrate salt of pentolinium. It has a role as an antihypertensive agent. It contains a pentolinium ion.
Names & identifiers
- Preferred name
- Pentolinium Tartrate
- IUPAC
- 1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium;bis((2R,3R)-2,3,4-trihydroxy-4-oxobutanoate)
Names & synonyms
PENTOLINIUM TARTRATEAnsolysenPentolonium tartrateRecurylTensilestPentalinium tartrateTartrato de pentolonioTartrate de pentoloniumPentolonii tartrasPentapyrrolidium bitartrate953357GACYPentamethylene-1,5-bis(1'-methylpyrrolidinium tartrate)
Show more names
NSC-759890CHEBI:55326pentolonio tartratopentolonium (cation)Tartrate, PentoliniumTartrate, PentoloniumRefChem:57597Pyrrolidinium, 1,1'-(1,5-pentanediyl)bis(1-methyl)-, salt with (R-(R*,R*))-2,3-dihydroxybutanedioic acid (1:2)
Database identifiers
- CAS
52-62-0- PubChem CID
- 5849
- ChEMBL
CHEMBL1318287- ChEBI
CHEBI:55326- UNII
- 953357GACY
Properties
Computed structural properties
- Topological polar surface area
- 236 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 10
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 347
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
Related reactions
0 records
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Compound notes
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