Basic information
- CAS
329-63-5- Standard SMILES
CNCC(O)c1ccc(O)c(O)c1.Cl- InChIKey
ATADHKWKHYVBTJ-UHFFFAOYSA-N- Molecular formula
- C9H14ClNO3
- Average molar mass
- 219.66 g/mol
- Monoisotopic mass
- 219.06622099
Overview
Racepinephrine Hydrochloride is an organic molecular entity.
Names & identifiers
- Preferred name
- (+-)-Epinephrine hydrochloride
- IUPAC
- 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride
- English name
- DL-Adrenaline hydrochloride
- Molecular formula
- C9H14ClNO3
- Molecular weight
- 219.67
Names & synonyms
329-63-5Racepinephrine hydrochlorideAsthmanefrin(+-)-Epinephrine hydrochlorideRacepinephrine HClRacepinefrine hydrochlorideAdrenaline hydrochloride, dl-Epinephrine hydrochloride, dl-336096P2WE1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochlorideEPINEPHRINE DL-FORM HYDROCHLORIDEEPINEPHRINE,RACEMIC HYDROCHLORIDE
Show more names
RAC EPINEPHRINE HCLDL-EPINEPHRINE HYDROCHLORIDEDL-EpinephAdrenalin HCLAdrenaline HCLEpinephrin HClDL-adrenaline hclrs-epinephrine hclTIMTEC-BB SBB003360Racepinephrine HydrochL
1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, hydrochlorideEpi-MistS2 RacepinephrineRefChem:55960S2 Racepinephrine MULTI-DOSE206-346-0DL-ADRENALINE HYDROCHLORIDE(+/-)-Epinephrine hydrochloride
Database identifiers
Properties
Computed structural properties
- Topological polar surface area
- 72.7 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 154
Physicochemical properties
- Melting point
- 157 ° · 157°
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: >50 mg/mL
- form
- A crystalline solid
- Water Solubility
- 2 O: · H2O: 50mg/mL
- Merck
- 14 · 14,3619
- Stability
- Stable, but light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
- InChI
- InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H
- InChIKey
- ATADHKWKHYVBTJ-UHFFFAOYSA-N
- SMILES
- C1(C(O)CNC)=CC=C(O)C(O)=C1.Cl
- CAS DataBase Reference
- 329 · 329-63-5(CAS DataBase Reference)
- FDA UNII
- 336096 P2WE · 336096P2WE
- EPA Substance Registry System
- (+-)-Epinephrine hydrochloride (329-63-5)
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 77 · NA.77
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (97.6%): Toxic if swallowed [Danger Acute toxicity, oral]
P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information1,2-Benzenediol, 4-1-hydroxy-2-(methylamino)ethyl-, hydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 3 (97.6%)
Safety data
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- DO3330000
- ridadr
- UN 2811 6.1/PG 2
- hs_code
- 2937901500
- risk_code
- 24/25-36/37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- T
- safety_code
- 26-36/37-45
- hazard_class
- 6.1(a)
- Storage Class
- 3 - Flammable liquids
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that selectively bind to and activate alpha adrenergic receptors.
Drugs that selectively bind to and activate beta-adrenergic receptors.
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Drugs used to cause constriction of the blood vessels.
Uses & manufacturing
General Manufacturing Information1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (1:1): ACTIVE
Applications
UsesAn adrenergic receptor agonist.
Uses(±)-Epinephrine hydrochloride has been used:in the induction of renalase expression in Human renal proximal tubular epithelial cellsin the infusion studies to test its effect on heart rate and eye temperature measurements in bullas a medium supplement for the stimulation of endothelial progenitor cells
Usesbronchodilatator,
General DescriptionEpinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamine N-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney.
Suppliers
Related reactions
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Compound notes
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