Cytidine triphosphate disodium salt
CTP DISODIUM SALT · CTP.2Na · dTTP.Na2 · 5′-CTP，2 · CTPNa.2H2O · CTP, NA2H2 · 5′-CTP,2Na · 5'-CMP 2NA
Identifiers & Physical Properties
| CAS No. | 36051-68-0 |
|---|---|
| Molecular formula | C9H16N3O14P3 |
| Average molar mass | 483.16 g/mol |
| Monoisotopic mass | 482.98451208 g/mol |
| SMILES | Nc1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)n1 |
| InChIKey | PCDQPRRSZKQHHS-UHFFFAOYSA-N |
| PubChem CID | 593 |
| DTXSID | DTXSID20861610 |
Chemical & Physical Properties
| XLogP | -5.6 |
|---|---|
| Topological polar surface area | 268 |
| Hydrogen bond donors | 7 |
| Hydrogen bond acceptors | 14 |
| Rotatable bonds | 8 |
| Heavy atoms | 29 |
| Formal charge | 0 |
| Complexity | 855 |
| Flash point | 113 °C |
| Storage conditions | -20°C |
| Solubility | H2O: 50 mg/mL, clear, colorlessSoluble in water. Insoluble in ethanol, chloroform and ether. |
| Physical state | Powder |
| Color | White |
| InChIKey | LGADHEWLYMMGHW-RFFBCSJBNA-N |
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,19,r| |
| CAS DataBase Reference | 36051-68-0(CAS DataBase Reference) |
| FDA UNII | 7D7ZF20MNG |
| UNSPSC Code | 41106305 |
| NACRES | NA.77 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P305+P351+P338 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Safety statements (S) | 24/25 |
| Water hazard class (WGK) | 3 |
| F | 10-21 |
| Customs code | 29349990 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| F | 10-21 |
|---|---|
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| Customs code | 29349990 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Safety statements (S) | 24/25 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P305+P351+P338 |
Applications & Uses
Description
Cytidine 5'-triphosphate disodium salt is a nucleoside triphosphate with a pyrimidine ring, which is present in RNA. It is a nucleotide derivative and is involved in phospholipid anabolism in vivo. It can cross the blood-cerebrospinal fluid barrier. It is the intermediate product and energy source of cephalin synthesis and nucleic acid metabolism. It can also improve the stability and reconstruction ability of nerve cell membrane structure, support nerve cell survival, delay cell aging and death, and improve nerve cells. Injury resistance, promote neurite outgrowth.
Uses
Cytidine-5'-triphosphate disodium salt is a cation-permeable ligand gated ion channel (P2X purinergic receptor) agonist. It is also used as an organic intermediate, pharmaceutical intermediate, food additive and flavoring agent.
Uses
Cytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]
General Description
Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.