Basic information
- CAS
1026796-81-5- Standard SMILES
CC(=O)Nc1cc(Br)ccn1- InChIKey
LFMGMKPLBDZJLP-UHFFFAOYSA-N- Molecular formula
- C7H7BrN2O
- Average molar mass
- 215.05 g/mol
- Monoisotopic mass
- 213.97418
Names & identifiers
- Preferred name
- N-(4-Bromopyridin-2-yl)acetamide
- IUPAC
- N-(4-bromo-2-pyridinyl)acetamide
- English name
- N-(4-Bromo-2-pyridinyl)-acetamide
- Molecular formula
- C7H7BrN2O
- Molecular weight
- 215.05
Names & synonyms
N-(4-Bromopyridin-2-yl)acetamide1026796-81-5DTXSID00732319RefChem:361810DTXCID90683063828-637-7Acetamide, N-(4-bromo-2-pyridinyl)-N-(4-bromo-2-pyridyl)acetamideMFCD11976392SCHEMBL355579SCHEMBL29899021LFMGMKPLBDZJLP-UHFFFAOYSA-N
Show more names
N-(4-bromo-pyridin-2-yl)-acetamideAKOS016001773DS-3638N-(4-Bromopyridin-2-yl)acetamide[N/ADA-48278SY116307N-(4-BROMO-2-PYRIDINYL)-ACETAMIDECS-0153957
Database identifiers
- CAS
1026796-81-5- PubChem CID
- 59529635
- DTXSID
DTXSID00732319- EC Number
- 828-637-7
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 42 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 151
Physicochemical properties
- Boiling point
- 385.1 · 385.1±27.0 °C(Predicted)
- Density
- 1.63 · 1.630±0.06 g/cm3(Predicted)
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 13.15 · 13.15±0.70(Predicted)
- Appearance
- Off-white to light yellow Solid
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 335 · H335-H302-H315-H319
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H335-H302-H315-H319
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Chemistry & industry
Applications
UsesN-(4-Bromopyridin-2-yl)acetamide is used as a reactant in the preparation of trisubstituted pyridinylimidazoles as potent inhibitors of the clinically resistant L858R/T790M/C797S EGFR mutant.
Upstream & downstream products
Upstream raw materials
Suppliers31 total
河南多贝化工有限公司0370-6999054 17550096163 · [email protected]
Aladdin Scientific[email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
芷威（上海）化学科技有限公司021-20221225 13917446399 · [email protected]
上海凯盟化学科技有限公司18916626092 · [email protected]
常州科化生物科技有限公司0519-68985668 13685222090 · [email protected]
ChemeGen 中国18818260767 · [email protected]
Related reactions
4 records
Compound notes
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