Basic information
- CAS
298705-56-3- Standard SMILES
NCc1cnc(-c2ccccc2)s1- InChIKey
PKLIUDDDCZOCFU-UHFFFAOYSA-N- Molecular formula
- C10H10N2S
- Average molar mass
- 190.27 g/mol
- Monoisotopic mass
- 190.0564695
Names & identifiers
- Preferred name
- (2-Phenyl-1,3-thiazol-5-yl)methanamine
- IUPAC
- (2-phenyl-1,3-thiazol-5-yl)methanamine
- English name
- C-(2-PHENYL-THIAZOL-5-YL)-METHYLAMINE
- Molecular formula
- C10H10N2S
- Molecular weight
- 190.26
Names & synonyms
(2-Phenyl-1,3-thiazol-5-yl)methanamineRefChem:396217848-471-9298705-56-3(2-Phenylthiazol-5-yl)methanamineC-(2-PHENYL-THIAZOL-5-YL)-METHYLAMINE1-(2-phenyl-1,3-thiazol-5-yl)methanamineMFCD02853617[(2-Phenyl-1,3-thiazol-5-yl)methyl]amine dihydrochloride1-(2-phenyl-1,3-thiazol-5-yl)methanamine dihydrochloride5-Thiazolemethanamine, 2-phenyl-(2-PHENYL-THIAZOL-5-YL)METHYLAMINE
Show more names
(2-Phenylthiazol-5-yl)methylamine(2-phenyl-5-thiazolyl)methanamine(2-phenyl-1,3-thiazol-5-yl-methyl)amine
Thiazole-5-methanamine, 2-phenyl-2-PHENYL-5-THIAZOLEMETHANAMINESCHEMBL3492794DTXSID60344290PKLIUDDDCZOCFU-UHFFFAOYSA-NALBB-015192STK387247AKOS003274992
Database identifiers
- CAS
298705-56-3- PubChem CID
- 595758
- DTXSID
DTXSID60344290- EC Number
- 848-471-9
Properties
Computed structural properties
- XLogP
- 1.5
- Topological polar surface area
- 67.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 157
Physicochemical properties
- Boiling point
- 353.2 · 353.2±34.0 °C(Predicted)
- Density
- 1.208 · 1.208±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- pka
- 8.13 · 8.13±0.29(Predicted)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 335 · H335-H302-H315-H319
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H335-H302-H315-H319
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Chemistry & industry
Applications
Uses(2-Phenylthiazol-5-yl)methanamine is used as a reactant in the preparation of dihydrobenzofuran amides as γ-secretase modulators that lower Aβ42 in the brain and avoid P-glycoprotein mediated efflux.
Suppliers15 total
上海凛南医药科技有限公司15900633975;13262632028 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
山东李比希生物医药科技有限公司15318973357; 15318973357 · [email protected]
上海鑫圭生物科技有限公司15121041756 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
盐城希曼生物科技有限公司0515-88280676; 18921872653 · [email protected]
上海睿升化工科技有限公司15026594951 · [email protected]
成都塞欧斯医药科技有限公司028-64971018 18108168130
江苏艾康生物医药研发有限公司025-58859352 13913916777 · [email protected]
成都博科辰欣医药科技有限公司028-82393420 18108156287 · [email protected]
上海智乾生物科技有限公司[email protected]
北京蓝博特科技有限公司010-56330744 18310155299 · [email protected]
佰美济华（河南）医药科技有限公司0371-88900765 18037465274 · [email protected]
合肥钼凯医药科技有限公司18001872185; 18001872185 · [email protected]
南京世洲生物科技有限公司025-85563444 15850508050 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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