HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-ethyl-2-oxo-1-Pyrrolidineacetamide
UCB-6474 · ETIRACETAM · rac-Levetiracetam · Etiracetam USP/EP/BP · SALOR-INT L127760-1EA · Levetiracetam Racemate · (+-)-1-pyrrolidineacetamid · Levetiracetam Impurity CRS
Identifiers & Physical Properties
| CAS No. | 33996-58-6 |
|---|---|
| Molecular formula | C8H14N2O2 |
| Average molar mass | 170.21 g/mol |
| Monoisotopic mass | 170.10552769 g/mol |
| SMILES | CCC(C(N)=O)N1CCCC1=O |
| InChIKey | HPHUVLMMVZITSG-UHFFFAOYSA-N |
| PubChem CID | 59708 |
| ChEMBL | CHEMBL1400561 |
| ChEBI | CHEBI:176724 |
| EC No. | 642-997-0 |
| DTXSID | DTXSID5046510 |
Chemical & Physical Properties
| XLogP | -0.3 |
|---|---|
| Topological polar surface area | 63.4 |
| Hydrogen bond donors | 1 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 3 |
| Heavy atoms | 12 |
| Formal charge | 0 |
| Complexity | 203 |
| Melting point | 113-114 °C(Solv: acetone (67-64-1)) |
| Boiling point | 395.9±25.0 °C(Predicted) |
| Density | 1.168±0.06 g/cm3(Predicted) |
| Vapor pressure | 0Pa at 25℃ |
| Storage conditions | Store at -20°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly)401g/L at 20℃ |
| pKa (acidity coefficient) | 15.74±0.50(Predicted) |
| Physical state | Solid |
| Color | White to off-white |
| BRN | 1529106 |
| LogP (partition coefficient) | 0.7 at 20℃ |
| FDA UNII | 230447L0GL |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
| GHS pictogram | GHS07,GHS09 |
| Signal word | Warning |
| GHS hazard statements | H302-H319-H411 |
| GHS precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 |
| Hazard symbols | Xn,N |
| Risk statements (R) | 22-36-51/53 |
| Safety statements (S) | 26-61 |
| UN transport number | UN 3077 9 / PGIII |
| Customs code | 2933790002 |
| Toxicity | mouse,LD50,intravenous,1790mg/kg (1790mg/kg),United States Patent Document. Vol. #4696943, |
| REACH registrations | Active |
Safety & Regulations
| UN transport number | UN 3077 9 / PGIII |
|---|---|
| Customs code | 2933790002 |
| Toxicity | mouse,LD50,intravenous,1790mg/kg (1790mg/kg),United States Patent Document. Vol. #4696943, |
| Risk statements (R) | 22-36-51/53 |
| Signal word | Warning |
| GHS pictogram | GHS07,GHS09 |
| Hazard symbols | Xn,N |
| Safety statements (S) | 26-61 |
| GHS hazard statements | H302-H319-H411 |
| REACH registrations | Active |
| GHS precautionary statements | P264-P270-P273-P280-P301+P312-P305+P351+P338 |
Applications & Uses
Uses
A nootropic drug that produced a significant increase in β-wave activity and stimulated α-wave activity dose-dependently. Etiracetam has been used in studies to alleviate the effects of memory retrieval defic its in rats.