Basic information
- CAS
110311-27-8- Standard SMILES
O=C(Nc1ccc(Cl)cc1)NS(=O)(=O)c1ccc2c(c1)CCC2- InChIKey
JQJSFAJISYZPER-UHFFFAOYSA-N- Molecular formula
- C16H15ClN2O3S
- Average molar mass
- 350.8 g/mol
- Monoisotopic mass
- 350.0491912
Overview
Sulofenur is a small molecule drug. Sulofenur has a monoisotopic molecular weight of 350.05 Da.
Names & identifiers
- Preferred name
- Sulofenur
- IUPAC
- 1-(4-chlorophenyl)-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)urea
- English name
- Sulofenur
- Molecular formula
- C16H15ClN2O3S
- Molecular weight
- 350.82
Names & synonyms
SULOFENUR110311-27-8SulofenurumISCULY-186641LY186641DTXSID20149208Z45N070N3S1H-Indene-5-sulfonamide, N-(((4-chlorophenyl)amino)carbonyl)-2,3-dihydro-NSC656667N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)ureaRefChem:932399
Show more names
1-(p-Chlorophenyl)-3-(5-indanylsulfonyl)urea1-(Indan-5-ylsulfonyl)-3-(4-chlorophenyl)urea1H-Indene-5-sulfonamide, N-[[(4-chlorophenyl)amino]carbonyl]-2,3-dihydro-
DTXCID80716991-(4-chlorophenyl)-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)ureaNSC645012N-(Indanyl-5-sulfonyl)-N'-(4-chlorophenyl)ureaNSC 642684; NSC 645012; NSC 656667N-((4-chlorophenyl)carbamoyl)-2,3-dihydro-1H-indene-5-sulfonamideSulofenurum [INN-Latin]LY 186641
Database identifiers
- CAS
110311-27-8- PubChem CID
- 60417
- DTXSID
DTXSID20149208- ChEMBL
CHEMBL7643- UNII
- Z45N070N3S
- Nikkaji
- J345.437A
Properties
Computed structural properties
- XLogP
- 4.4
- Topological polar surface area
- 83.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 3
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 526
Physicochemical properties
- Melting point
- 169 · 169-172 °C
- FDA UNII
- 45 N070N3S · Z45N070N3S
- NCI Drug Dictionary
- sulofenur
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances that inhibit or prevent the proliferation of NEOPLASMS.
Applications
UsesAntineoplastic.
UsesSulofenur can be used for preventing or treating cancer and autoimmune disorders, where it can be used as conjoint therapy for immunomodulation.
Suppliers5 total
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
湖北扬信医药科技有限公司15347293736 · [email protected]
上海德轩医药科技有限公司[email protected] · [email protected]
武汉多普乐生物医药有限公司+86-02787215551 19945035818 · [email protected]
Related reactions
5 records
Compound notes
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