Basic information
- CAS
13085-08-0- Standard SMILES
CN1CCN(CC(=O)[C@@]2(O)CC[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@@]32C)CC1- InChIKey
CZBOZZDZNVIXFC-VRRJBYJJSA-N- Molecular formula
- C26H38N2O4
- Average molar mass
- 442.6 g/mol
- Monoisotopic mass
- 442.2831577
Overview
Mazipredone is a corticosteroid hormone.
Names & identifiers
- Preferred name
- Mazipredone
- IUPAC
- (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-17-[2-(4-methylpiperazin-1-yl)acetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
- English name
- Mazipredone
- Molecular formula
- C26H38N2O4
- Molecular weight
- 442.59
Names & synonyms
MazipredoneMazipredona13085-08-0MazipredonumQN0W2YSW63DTXSID3092694111beta,17-Dihydroxy-21-(4-methyl-1-piperazinyl)pregna-1,4-diene-3,20-dioneRefChem:156029DTXCID001355747Mazipredone [INN](8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-17-[2-(4-methylpiperazin-1-yl)acetyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-oneMazipredone (INN)
Show more names
11β,17α-Dihydroxy-21-(4-methylpiperazin-1-yl)pregna-1,4-diene-3,20-dionePregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(4-methyl-1-piperazinyl)-, (11β)-11,17-Dihydroxy-10,13-dimethyl-17-(2-(4-methylpiperazin-1-yl)acetyl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
UNII-QN0W2YSW63Mazipredone (free base)MAZIPREDONE [MI]MAZIPREDONE [MART.]SCHEMBL25720MAZIPREDONE [WHO-DD]orb1696181CHEMBL2106858
Properties
Computed structural properties
- XLogP
- 1.6
- Topological polar surface area
- 81.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 3
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 875
Physicochemical properties
- FDA UNII
- 0 W2YSW63 · QN0W2YSW63
Chemistry & industry
Applications
UsesMazipredone free base, a glucocorticoid derivative, is an anti-inflammatory and anti-allergic agent. Mazipredone free base is sensitive to oxidation, acidic and basic media[1].
Suppliers4 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
Alchem Pharmtech,Inc.8485655694 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
Additional notes
DefinitionChEBI: Mazipredone is a corticosteroid hormone.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…