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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 60712Generated: October 23, 2026

Tenidap

TENIDAP · AKOS 91367 · TENIDAP USP/EP/BP · CP66248,CP-66248-2 · 5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide · (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide · (3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide · (3Z)-5-CHLORO-3-[HYDROXY(2-THIENYL)METHYLENE]-2-OXO-2,3-DIHYDRO-1H-INDOLE-1-CARBOXAMIDE

https://huagongshe.com/en/chemical/60712

Tenidap molecular structure

Identifiers & Physical Properties

CAS No.120210-48-2
Molecular formulaC14H9ClN2O3S
Average molar mass320.8 g/mol
Monoisotopic mass320.00224083 g/mol
SMILESNC(=O)n1c(O)c(C(=O)c2cccs2)c2cc(Cl)ccc21
InChIKeyIZSFDUMVCVVWKW-UHFFFAOYSA-N
PubChem CID60712
ChEMBLCHEMBL1097558
ChEBICHEBI:35847
DTXSIDDTXSID9046104

Chemical & Physical Properties

XLogP3.8
Topological polar surface area114
Hydrogen bond donors2
Hydrogen bond acceptors4
Rotatable bonds2
Heavy atoms21
Formal charge0
Complexity450
Melting point230° (dec)
Boiling point538.1±60.0 °C(Predicted)
Density1.648±0.06 g/cm3(Predicted)
Storage conditionsStore at +4°C
SolubilityDMSO: soluble1mg/mL, clear (warmed)
Physical statepowder
pKa (acidity coefficient)4.50±1.00(Predicted)
Colorfaint yellow to dark yellow
InChI1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20)
InChIKeyIZSFDUMVCVVWKW-UHFFFAOYSA-N
SMILES[s]1c(ccc1)C(=O)c2c3c([n](c2O)C(=O)N)ccc(c3)Cl
FDA UNII9K7CJ74ONH
ATC codeM01AX23
UNSPSC Code12352200
NACRESNA.77
GHS pictogramGHS07
Signal wordWarning
GHS hazard statementsH302
GHS precautionary statementsP264-P270-P301+P312-P501
Hazard symbolsXn
Risk statements (R)22
Water hazard class (WGK)3
Storage class11 - Combustible Solids
Hazard classAcute Tox. 4 Oral

Safety & Regulations

Water hazard class (WGK)3
Risk statements (R)22
Signal wordWarning
GHS pictogramGHS07
Hazard symbolsXn
Storage class11 - Combustible Solids
GHS hazard statementsH302
Hazard classAcute Tox. 4 Oral
GHS precautionary statementsP264-P270-P301+P312-P501

Applications & Uses

Uses

Anti-inflammatory (osteoarthritis and rheumatoid arthritis).

Uses

Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.