Basic information
- CAS
61-12-1- Standard SMILES
CCCCOc1cc(C(=O)NCC[NH+](CC)CC)c2ccccc2n1.[Cl-]- InChIKey
IVHBBMHQKZBJEU-UHFFFAOYSA-N- Molecular formula
- C20H30ClN3O2
- Average molar mass
- 379.9 g/mol
- Monoisotopic mass
- 379.2026549
Overview
Cinchocaine hydrochloride is the monohydrochloride salt of cinchocaine. It is used in creams, ointments and suppositories for temporary relief of pain and itching associated with skin and anorectal conditions. It contains a cinchocaine.
Names & identifiers
- Preferred name
- 2-[(2-Butoxyquinoline-4-carbonyl)amino]ethyl-diethylazanium;chloride
- IUPAC
- 2-[(2-butoxyquinoline-4-carbonyl)amino]ethyl-diethylazanium chloride
- English name
- Dibucaine hydrochloride
- Molecular formula
- C20H30ClN3O2
- Molecular weight
- 379.92
Names & synonyms
AKOS0267498762-[(2-butoxyquinoline-4-carbonyl)amino]ethyl-diethylazanium;chlorideCINCHOCAINE HYDROCHLORIDECINCHOCAINE HCLDIBUCAINE HCLc3225percainsovcainpercainesovcaineCincainepercamins
Database identifiers
- CAS
61-12-1- PubChem CID
- 6078
- ChEBI
CHEBI:59735
Properties
Computed structural properties
- Topological polar surface area
- 55.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 10
- Heavy atoms
- 26
- Formal charge
- 0
- Complexity
- 387
Experimental & physicochemical properties
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Physicochemical properties
- Melting point
- 99 · 99-101 °C(lit.)
- Density
- 1.1338 · 1.1338 (rough estimate)
- refractive index
- 1.54 · 1.5400 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Hygroscopic crystals
- PH
- pH(20g/l,25℃) : 5.0～6.0
- Water Solubility
- Freely soluble in water, alcohol, acetone, or chloroform
- Merck
- 13 · 13,3057
- Stability
- Stable. Incompatible with strong oxidizing agents. Protect from moisture.
- Major Application
- forensics and toxicologypharmaceutical (small molecule)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Faceshields, Gloves
- wgk
- 3
- rtecs
- GD3325000
- hs_code
- 2933492250
- Toxicity
- eye-rbt 2% SEV ARZNAD 8,181,58
- risk_code
- 22-41
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS07
- hazard_code
- Xn
- safety_code
- 26-39
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H318
- Precautionary statements
- P280-P301+P312+P330-P305+P351+P338+P310
Chemistry & industry
Applications
UsesAnesthetic (local).
UsesCinchocaine is used as an anaesthetic agent for spinal anaesthesia; a component in rectal medications used in inflammation of the anus and for the symptomatic treatment of hemorrhoids and fissures in the anus; local anesthetic agent.
UsesDibucaine HCl is an amide-like quinoline derivative and is one of the most potent and longest acting of the commonly used local anesthetics.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
济南诚汇双达生物有限公司053158897070 15550412551 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
山东雨禾医药科技有限公司15263077727 · [email protected]
上海毕得医药科技股份有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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