Basic information
- CAS
136816-75-6- Standard SMILES
CCNc1cccnc1N1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)CC1- InChIKey
UCPOMLWZWRTIAA-UHFFFAOYSA-N- Molecular formula
- C21H25N5O2
- Average molar mass
- 379.5 g/mol
- Monoisotopic mass
- 379.20082506
Overview
Atevirdine has been used in trials studying the treatment of HIV Infections.
Names & identifiers
- Preferred name
- Atevirdine
- IUPAC
- [4-[3-(ethylamino)-2-pyridinyl]piperazin-1-yl]-(5-methoxy-1H-indol-2-yl)methanone
- English name
- atevirdine
- Molecular formula
- C21H25N5O2
- Molecular weight
- 379.46
Names & synonyms
Atevirdine136816-75-6AtevirdinaN24015WC6DDTXSID40159940Piperazine, 1-(3-(ethylamino)-2-pyridinyl)-4-((5-methoxy-1H-indol-2-yl)carbonyl)-Piperazine, 1-[3-(ethylamino)-2-pyridinyl]-4-[(5-methoxy-1H-indol-2-yl)carbonyl]-atevirdinumRefChem:560303U-87201DTXCID1082431N-ethyl-2-(4-(5-methoxy-1H-indole-2-carbonyl)piperazin-1-yl)pyridin-3-amine
Show more names
Guanosine 5′-(tetrahydrogen triphosphate), 7-methyl-, inner salt (9CI, ACI)Methanone, [4-[3-(ethylaMino)-2-pyridinyl]-1-piperazinyl](5-Methoxy-1H-indol-2-yl)-
Atevirdine [INN]CHEMBL280527(4-(3-(ethylamino)pyridin-2-yl)piperazin-1-yl)(5-methoxy-1H-indol-2-yl)methanone[4-[3-(ethylamino)pyridin-2-yl]piperazin-1-yl]-(5-methoxy-1H-indol-2-yl)methanone1-[(5-Methoxyindol-2-yl)carbonyl]-4-[3-(ethylamino)-2-pyridyl]piperazine[4-[3-(ethylamino)-2-pyridyl]piperazin-1-yl]-(5-methoxy-1H-indol-2-yl)methanoneUNII-N24015WC6D{4-[3-(Ethylamino)pyridin-2-yl]piperazin-1-yl}(5-methoxy-1H-indol-2-yl)methanone
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 3
- Topological polar surface area
- 73.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 525
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Melting point
- 153 · 153-154°
- form
- Solid
- color
- White to light yellow
- FDA UNII
- 24015 WC6D · N24015WC6D
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationInhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
Applications
UsesAntiviral.
Upstream & downstream products
Upstream raw materials
Suppliers14 total
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
上海眷开生物医药有限公司15052267297 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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