Basic information
- CAS
66969-81-1- Standard SMILES
COc1cc2nc(N3CCN(C(=O)c4nnc(SC)o4)CC3)nc(N)c2cc1OC- InChIKey
MULPYFRDYRZMDS-UHFFFAOYSA-N- Molecular formula
- C18H21N7O4S
- Average molar mass
- 431.5 g/mol
- Monoisotopic mass
- 431.13757335
Overview
Tiodazosin is a N-arylpiperazine.
Names & identifiers
- Preferred name
- Tiodazosin
- IUPAC
- [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)methanone
- English name
- Tiodazosin
- Molecular formula
- C18H21N7O4S
- Molecular weight
- 431.47
Names & synonyms
Tiodazosin66969-81-1TiodazosinaTiodazosineTiodazosinumBL-5111FQI0PYJ799DTXSID90217180RefChem:933090DTXCID901396714-amino-6,7-dimethoxy-2-4-(5-methylthio-1,3,4-oxadiazole-2-carbonyl)piperazin-1-yl quinazoline[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)methanone
Show more names
Tiodazosi1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[5-(methylthio)-1,3,4-oxadiazol-2-yl]carbonyl]piperazineMethanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][5-(methylthio)-1,3,4-oxadiazol-2-yl]-
(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(5-(methylthio)-1,3,4-oxadiazol-2-yl)methanone1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((5-(methylthio)-1,3,4-oxadiazol-2-yl)carbonyl)-piperazineTiodazosin [USAN:INN]Tiodazosine [INN-French]Tiodazosinum [INN-Latin]UNII-FQI0PYJ799Tiodazosina [INN-Spanish]1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[5-(methylthio)-1,3,4-oxadiazol-2-yl]carbonyl]-piperazine
Database identifiers
Properties
Computed structural properties
- XLogP
- 1.6
- Topological polar surface area
- 158 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 5
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 597
Physicochemical properties
- Boiling point
- 690.2 · 690.2±65.0 °C(Predicted)
- Density
- 1.5 · 1.50±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 6.52 · 6.52±0.50(Predicted)
- FDA UNII
- 0 PYJ799 · FQI0PYJ799
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesTiodazosin, is a potent competitive postsynaptic alpha adrenergic receptor antagonist.
Suppliers9 total
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
上海芮晖化工科技有限公司021-31433387 15618786686 · [email protected]
范德(北京)生物科技有限责任公司15911056312 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
佛山合硕医药科技有限公司15363639686 · [email protected]
Additional notes
DefinitionChEBI: Tiodazosin is a N-arylpiperazine.
Related reactions
2 records
Compound notes
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