Basic information
- CAS
76541-72-5- Standard SMILES
COP(=O)(OC)OC(c1ccc(Cl)cc1)P(=O)(OC)OC- InChIKey
VQHUQHAPWMNBLP-UHFFFAOYSA-N- Molecular formula
- C11H17ClO7P2
- Average molar mass
- 358.65 g/mol
- Monoisotopic mass
- 358.0138046
Overview
Phosphoric acid [(4-chlorophenyl)-dimethoxyphosphorylmethyl] dimethyl ester is a trialkyl phosphate.
Names & identifiers
- Preferred name
- Mifobate
- IUPAC
- [(4-chlorophenyl)-dimethoxyphosphorylmethyl] dimethyl phosphate
- English name
- SR 202
- Molecular formula
- C11H17ClO7P2
- Molecular weight
- 358.65
Names & synonyms
Mifobate76541-72-5ClenicorSR-202MifobatoCLANICLORMifobatumDTXSID6045741ZKA4OVV12EPhosphoric acid, (4-chlorophenyl)(dimethoxyphosphinyl)methyl dimethyl esterDTXCID4025741RefChem:925883
Show more names
SR-202 >=98% (HPLC), crystallineDimethyl (α-dimethoxyphosphinyl-p-chlorobenzyl) phosphateDIMETHYL (ALPHA-DIMETHOXYPHOSPHINYL-P-CHLOROBENZYL) PHOSPHATE[(4-Chlorophenyl)(dimethoxyphosphinyl)methyl]dimethyl=phosphateDimethyl (α-dimethoxyphosphinyl-p-chlorobenzyl) phosphate, Mifobate
dimethyl alpha-(dimethoxyphosphinyl)-4-chlorobenzyl phosphate(4-chlorophenyl)(dimethoxyphosphinyl)methylphosphoric acid dimethyl esterSR 202(4-chlorophenyl)(dimethoxyphosphoryl)methyl dimethyl phosphate(4-Chlorophenyl)(dimethoxyphosphinyl)methyl phosphoric acid dimethyl ester[(4-chlorophenyl)-dimethoxyphosphorylmethyl] dimethyl phosphateCHEMBL284768NCGC00092299-01
Database identifiers
- CAS
76541-72-5- PubChem CID
- 60910
Properties
Computed structural properties
- XLogP
- 1
- Topological polar surface area
- 80.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 395
Physicochemical properties
- Boiling point
- 436.6 · 436.6±45.0 °C(Predicted)
- Density
- 1.355 · 1.355±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Inert atmosphere,Store in freezer, under -20°C
- solubility
- 5 mg/mL · DMSO: 5 mg/mL
- form
- crystalline
- color
- white
- Water Solubility
- 100 mM · Soluble to 100 mM in water
- FDA UNII
- 4 OVV12E · ZKA4OVV12E
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
- Safety Statements
- 22 · 22-24/25
- WGK Germany
- 2 · 2
- RTECS
- 8817000 · TB8817000
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 2
- rtecs
- TB8817000
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 22-24/25
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Chemistry & industry
Applications
DescriptionSR 202 is an effective and specific PPARγ antagonist that selectively inhibits the transcriptional activity of PPARγ induced by TZD (IC50=140 μM). Sr-202 does not affect basal or ligand stimulated transcriptional activity of PPARα, PPARβ, or FXR. It has anti-obesity and anti-diabetes effects.
UsesAnti-atherosclerotic.
UsesSR 202 is a noniodinated, potential lipid-altering agent and an inhibitor of the peripheral conversion of T4 to T3 associated with thyroid hormone metabolism.
Suppliers36 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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